Bibliographic Details
Title: |
Anticholinergic Burden and Dry Mouth Problems Among Older Adults (≥ 50 Years) Receiving Dental Care—A Retrospective, Cross‐Sectional Analysis |
Authors: |
Christoph Matthias Schoppmeier, Isabel Deeg, Michael Jochen Wicht, Anna Greta Barbe |
Source: |
Clinical and Experimental Dental Research, Vol 10, Iss 6, Pp n/a-n/a (2024) |
Publisher Information: |
Wiley, 2024. |
Publication Year: |
2024 |
Collection: |
LCC:Dentistry |
Subject Terms: |
elderly, German anticholinergic burden score, hyposalivation, xerostomia, Dentistry, RK1-715 |
More Details: |
ABSTRACT Objectives Anticholinergics cause dry mouth and are highly relevant for dentists, but little is known about the relationships between intake and the occurrence of subjective and objective dry mouth with age. The German anticholinergic burden score (GACB) is a novel anticholinergic score that re‐evaluates medications, particularly, those with classification discrepancies. Material and Methods We retrospectively investigated the GACB in older patients receiving dental care, evaluated whether GACB is related to xerostomia and unstimulated salivary secretion, and determined the influence of increasing age (beginning at 50 years of age). The GACB score quantified cumulative anticholinergic effects: 0 for no effect, 1 for possible, 2 for moderate, and 3 for strong. Cross‐sectional data in patients ≥ 50 years were collected, including xerostomia with the visual analog scale, unstimulated salivary flow rates, and the GACB scores. Results Among 172 patients (mean age 65.67 ± 9.51 years), 23.8% had a GACB score ≥ 1. A moderate negative correlation was observed between GACB and unstimulated salivary flow rates (r̅ = −0.51). Patients with GACB ≥ 1 had fewer teeth (mean 21.76 ± 5.41) than those with GACB = 0 (24.07 ± 5.57). Moreover, unstimulated hyposalivation was observed in 61.0% with GACB ≥ 1 versus 6.8% with GACB = 0 (p |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2057-4347 |
Relation: |
https://doaj.org/toc/2057-4347 |
DOI: |
10.1002/cre2.70009 |
Access URL: |
https://doaj.org/article/1fcc4ce8d6e4413597616e537fbb055e |
Accession Number: |
edsdoj.1fcc4ce8d6e4413597616e537fbb055e |
Database: |
Directory of Open Access Journals |