Effectiveness of platelet-rich plasma separation technique in total aortic arch replacement
| Title: | Effectiveness of platelet-rich plasma separation technique in total aortic arch replacement |
|---|---|
| Authors: | PANG Chao, ZHANG Shaopeng, BAI Yunpeng, XIE Shuhua |
| Source: | Zhongguo shuxue zazhi, Vol 38, Iss 2, Pp 189-193 (2025) |
| Publisher Information: | Institute of Blood Transfusion of Chinese Academy of Medical Sciences, 2025. |
| Publication Year: | 2025 |
| Collection: | LCC:Diseases of the blood and blood-forming organs LCC:Medicine |
| Subject Terms: | aortic dissection, blood transfusion, platelet-rich plasma, Diseases of the blood and blood-forming organs, RC633-647.5, Medicine |
| More Details: | [Objective] To evaluate the efficacy and practicality of autologous platelet-rich plasma (aPRP) in patients undergoing total aortic arch replacement for aortic dissection. [Methods] A retrospective analysis was performed on 483 patients diagnosed with type A aortic dissection who underwent total aortic arch replacement between January 2016 and November 2023. Patients were categorized into two groups based on whether they received aPRP. Baseline characteristics, intraoperative blood product usage and postoperative outcomes were compared between the two groups. [Results] The aPRP group exhibited reduced usage of allogeneic platelets (1.55±1.04 vs 1.60±1.27)U, allogeneic plasma (480.89±432.49 vs 746.50±508.81)mL, allogeneic RBC (red blood cell)(5.95±1.91 vs 6.17±3.52)U, bivalirudin (2.66±1.51 vs 3.31±1.59)U and coagulation factor Ⅶ (0.67±1.03 vs 1.22±1.43)mg compared to the non-aPRP group (P0.05). [Conclusion] The application of aPRP in total aortic arch replacement effectively diminishes intraoperative blood product usage and the incidence of lung injury-related complications. However, it does not demonstrate significant benefits in terms of mortality, cerebral infarction and other complications. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | Chinese |
| ISSN: | 1004-549X 1004-549x |
| Relation: | https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2025.02.005&lang=en; https://doaj.org/toc/1004-549X |
| DOI: | 10.13303/j.cjbt.issn.1004-549x.2025.02.005&lang=en |
| DOI: | 10.13303/j.cjbt.issn.1004-549x.2025.02.005 |
| Access URL: | https://doaj.org/article/1f2c6174cd344c33966ecafae042fc2e |
| Accession Number: | edsdoj.1f2c6174cd344c33966ecafae042fc2e |
| Database: | Directory of Open Access Journals |
| ISSN: | 1004549X 1004549x |
|---|---|
| DOI: | 10.13303/j.cjbt.issn.1004-549x.2025.02.005&lang=en |
| Published in: | Zhongguo shuxue zazhi |
| Language: | Chinese |