Academic Journal
Prospective, historically controlled study to evaluate the efficacy and safety of a new paediatric formulation of nifurtimox in children aged 0 to 17 years with Chagas disease one year after treatment (CHICO).
| Title: | Prospective, historically controlled study to evaluate the efficacy and safety of a new paediatric formulation of nifurtimox in children aged 0 to 17 years with Chagas disease one year after treatment (CHICO). |
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| Authors: | Jaime Altcheh, Luis Castro, Juan C Dib, Ulrike Grossmann, Erya Huang, Guillermo Moscatelli, Jimy José Pinto Rocha, Teresa Estela Ramírez, CHICO Study Group |
| Source: | PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e0008912 (2021) |
| Publisher Information: | Public Library of Science (PLoS), 2021. |
| Publication Year: | 2021 |
| Collection: | LCC:Arctic medicine. Tropical medicine LCC:Public aspects of medicine |
| Subject Terms: | Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270 |
| More Details: | Nifurtimox is a recommended treatment for Chagas disease, but data from treated children are limited. We investigated the efficacy, safety and tolerability of nifurtimox administered as divisible, dispersible 30 mg and 120 mg tablets in children with Chagas disease. In this blinded, controlled study conducted January 2016-July 2018, 330 patients aged |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1935-2727 1935-2735 |
| Relation: | https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735 |
| DOI: | 10.1371/journal.pntd.0008912 |
| Access URL: | https://doaj.org/article/1dcc32d8cefc4129bba991b7e817b145 |
| Accession Number: | edsdoj.1dcc32d8cefc4129bba991b7e817b145 |
| Database: | Directory of Open Access Journals |
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| ISSN: | 19352727 19352735 |
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| DOI: | 10.1371/journal.pntd.0008912 |
| Published in: | PLoS Neglected Tropical Diseases |
| Language: | English |