Bibliographic Details
| Title: |
Biliary obstruction and pancreatitis after duodenal stent placement in the descending duodenum: a retrospective study |
| Authors: |
Junichi Kaneko, Hirotoshi Ishiwatari, Koiku Asakura, Tatsunori Satoh, Junya Sato, Kazuma Ishikawa, Hiroyuki Matsubayashi, Yohei Yabuuchi, Yoshihiro Kishida, Masao Yoshida, Sayo Ito, Noboru Kawata, Kenichiro Imai, Kohei Takizawa, Kinichi Hotta, Hiroyuki Ono |
| Source: |
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-9 (2022) |
| Publisher Information: |
BMC, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Diseases of the digestive system. Gastroenterology |
| Subject Terms: |
Gastric outlet obstruction, Self-expandable metallic stent, Duodenal stent, Biliary obstruction, Pancreatitis, Diseases of the digestive system. Gastroenterology, RC799-869 |
| More Details: |
Abstract Background Metallic stents placed in the descending duodenum can cause compression of the major duodenal papilla, resulting in biliary obstruction and pancreatitis. These are notable early adverse events of duodenal stent placement; however, they have been rarely examined. This study aimed to assess the incidence of and risk factors for biliary obstruction and/or pancreatitis after duodenal stent placement in the descending duodenum. Methods We retrospectively reviewed data of consecutive patients who underwent metallic stent placement in the descending duodenum for malignant gastric outlet obstruction at a tertiary referral cancer center between April 2014 and December 2019. Risk factors for biliary obstruction and/or pancreatitis were analyzed using a logistic regression model. Results Sixty-five patients were included. Biliary obstruction and/or pancreatitis occurred in 12 patients (18%): 8 with biliary obstruction, 2 with pancreatitis, and 2 with both biliary obstruction and pancreatitis. Multivariate analysis indicated that female sex (odds ratio: 9.2, 95% confidence interval: 1.4–58.6, P = 0.02), absence of biliary stents (odds ratio: 12.9, 95% confidence interval: 1.8–90.2, P = 0.01), and tumor invasion to the major duodenal papilla (odds ratio: 25.8, 95% confidence interval: 2.0–340.0, P = 0.01) were significant independent risk factors for biliary obstruction and/or pancreatitis. Conclusions The incidence of biliary obstruction and/or pancreatitis after duodenal stent placement in the descending duodenum was non-negligible. Female sex, absence of biliary stents, and tumor invasion to the major duodenal papilla were the primary risk factors. Risk stratification can allow endoscopists to better identify patients at significant risk and permit detailed informed consent. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1471-230X |
| Relation: |
https://doaj.org/toc/1471-230X |
| DOI: |
10.1186/s12876-022-02333-7 |
| Access URL: |
https://doaj.org/article/ece1cf57498e4b3db372fbaa63a1e1c7 |
| Accession Number: |
edsdoj.1cf57498e4b3db372fbaa63a1e1c7 |
| Database: |
Directory of Open Access Journals |
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