Impact of periodic neck ultrasonography on locoregional disease control in surveillance after total thyroidectomy for patients with low- and intermediate-risk papillary thyroid carcinoma: a propensity score-matched study

Bibliographic Details
Title: Impact of periodic neck ultrasonography on locoregional disease control in surveillance after total thyroidectomy for patients with low- and intermediate-risk papillary thyroid carcinoma: a propensity score-matched study
Authors: Takahiro Inaishi, Dai Takeuchi, Takahiro Ichikawa, Gai Inaguma, Atsushi Hashizume, Masaki Okazaki, Norikazu Masuda, Toyone Kikumori
Source: Endocrine Journal, Vol 71, Iss 12, Pp 1135-1143 (2024)
Publisher Information: The Japan Endocrine Society, 2024.
Publication Year: 2024
Collection: LCC:Diseases of the endocrine glands. Clinical endocrinology
Subject Terms: locoregional recurrence, papillary thyroid carcinoma, surveillance, total thyroidectomy, ultrasonography, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
More Details: This study aimed to evaluate the impact of periodic neck ultrasonography (US) on postoperative surveillance for locoregional disease control of patients with low- and intermediate-risk papillary thyroid carcinoma (PTC) who underwent total thyroidectomy. This retrospective cohort study included patients with PTC who underwent total thyroidectomy and central neck dissection at our institution between January, 2000 and December, 2016. The patients were divided into two groups: the physical examination (PE) group (follow-up by PE without periodic US) and the US group (follow-up by PE with periodic US). Serum thyroglobulin levels were measured periodically in both groups. Propensity score matching was used to rigorously balance the significant variables and assess the 10-year postoperative outcomes between the groups. Of the 189 patients, 150 were included after matching (75 in each group). There were no significant differences between the two groups in terms of background characteristics. The median follow-up period was 127.9 months. There was no significant difference in locoregional relapse-free survival between the PE and US groups (97.0 vs. 98.7%, p = 0.541). The overall survival was 96.7% and 98.7% in the PE and US groups, respectively, with no significant difference (p = 0.364). This study demonstrated that the addition of periodic US to PE for postoperative surveillance of patients with low- and intermediate-risk PTC who underwent total thyroidectomy did not significantly affect locoregional control.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1348-4540
Relation: https://www.jstage.jst.go.jp/article/endocrj/71/12/71_EJ24-0194/_html/-char/en; https://doaj.org/toc/1348-4540
DOI: 10.1507/endocrj.EJ24-0194
Access URL: https://doaj.org/article/1cc0454a9e304c17af3fbbd7cfdfc921
Accession Number: edsdoj.1cc0454a9e304c17af3fbbd7cfdfc921
Database: Directory of Open Access Journals
More Details
ISSN:13484540
DOI:10.1507/endocrj.EJ24-0194
Published in:Endocrine Journal
Language:English