Mortality burden based on the associations of ambient PM2.5 with cause-specific mortality in China: Evidence from a death-spectrum wide association study (DWAS)

Bibliographic Details
Title: Mortality burden based on the associations of ambient PM2.5 with cause-specific mortality in China: Evidence from a death-spectrum wide association study (DWAS)
Authors: Tao Liu, Weiwei Gong, Chunliang Zhou, Guoxia Bai, Ruilin Meng, Biao Huang, Haoming Zhang, Yanjun Xu, Ruying Hu, Zhulin Hou, Yize Xiao, Junhua Li, Xiaojun Xu, Donghui Jin, Mingfang Qin, Qinglong Zhao, Yiqing Xu, Jianxiong Hu, Jianpeng Xiao, Guanghao He, Zuhua Rong, Fangfang Zeng, Pan Yang, Dan Liu, Lixia Yuan, Ganxiang Cao, Zhiqing Chen, Siwen Yu, Shangfeng Yang, Cunrui Huang, Yaodong Du, Min Yu, Lifeng Lin, Xiaofeng Liang, Wenjun Ma
Source: Ecotoxicology and Environmental Safety, Vol 259, Iss , Pp 115045- (2023)
Publisher Information: Elsevier, 2023.
Publication Year: 2023
Collection: LCC:Environmental pollution
LCC:Environmental sciences
Subject Terms: Air pollution, Cause-specific association, Mortality burden, Environmental pollution, TD172-193.5, Environmental sciences, GE1-350
More Details: Although studies have estimated the associations of PM2.5 with total mortality or cardiopulmonary mortality, few have comprehensively examined cause-specific mortality risk and burden caused by ambient PM2.5. Thus, this study investigated the association of short-term exposure to PM2.5 with cause-specific mortality using a death-spectrum wide association study (DWAS). Individual information of 5,450,764 deaths during 2013–2018 were collected from six provinces in China. Daily PM2.5 concentration in the case and control days were estimated by a random forest model. A time-stratified case-crossover study design was applied to estimate the associations (access risk, ER) of PM2.5 with cause-specific mortality, which was then used to calculate the population-attributable fraction (PAF) of mortality and the corresponding mortality burden caused by PM2.5. Each 10 μg/m3 increase in PM2.5 concentration (lag03) was associated with a 0.80 % [95 % confidence interval (CI): 0.73 %, 0.86 %] rise in total mortality. We found greater mortality effect at PM2.5 concentrations
Document Type: article
File Description: electronic resource
Language: English
ISSN: 0147-6513
Relation: http://www.sciencedirect.com/science/article/pii/S0147651323005493; https://doaj.org/toc/0147-6513
DOI: 10.1016/j.ecoenv.2023.115045
Access URL: https://doaj.org/article/1c3d7336a1774528844dd10002a595c6
Accession Number: edsdoj.1c3d7336a1774528844dd10002a595c6
Database: Directory of Open Access Journals
More Details
ISSN:01476513
DOI:10.1016/j.ecoenv.2023.115045
Published in:Ecotoxicology and Environmental Safety
Language:English