Bibliographic Details
| Title: |
Use of onsite typhoid IgG/IgM combo test as rapid diagnostic test for typhoid fever |
| Authors: |
Alaa Aboud Mohamed, Basel Abd El Monem Ebeid, Radwa Ahmed Rabea Abdellatif, Mariam Malak |
| Source: |
Beni-Suef University Journal of Basic and Applied Sciences, Vol 12, Iss 1, Pp 1-5 (2023) |
| Publisher Information: |
SpringerOpen, 2023. |
| Publication Year: |
2023 |
| Collection: |
LCC:Medicine (General)
LCC:Science |
| Subject Terms: |
Typhoid, Onsite typhoid IgG/IgM combo rapid test, Widal test, Blood culture, Medicine (General), R5-920, Science |
| More Details: |
Abstract Background The incidence of typhoid fever is increasing in Egypt. The Widal test is the evaluation most widely used in Egypt for diagnosis, but it has many drawbacks; therefore, new diagnostic tools are needed. Our aim was to evaluate the diagnostic accuracy of the onsite typhoid IgG/IgM combo rapid test in diagnosing typhoid fever. Method Blood specimens were collected from 90 patients (of all ages) who presented with fever of more than 4 days’ duration. The OnSite Combo test and the Widal test were performed for all patients. Results The OnSite Combo test results were positive in approximately 24% of all patients; the Widal test results were positive in 18.9%; and typhoid was diagnosed through blood culture in 32.2%. The OnSite Combo test had 72.4% sensitivity, 98.4% specificity, a positive predictive value of 95.5%, and a negative predictive value of 88.2%. In contrast, the Widal test had 51.7% sensitivity, 69.7% specificity, a positive predictive value of 88.2%, and a negative predictive value of 80.8%. Conclusions The onsite combo test was more efficacious than the Widal test in diagnosing typhoid fever. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2314-8543 |
| Relation: |
https://doaj.org/toc/2314-8543 |
| DOI: |
10.1186/s43088-023-00391-8 |
| Access URL: |
https://doaj.org/article/1bb21b7347874030924999e5082979fd |
| Accession Number: |
edsdoj.1bb21b7347874030924999e5082979fd |
| Database: |
Directory of Open Access Journals |
