| Title: |
Acute reverse annular remodeling during MitraClip® therapy predicts improved clinical outcome in heart failure patients: a 3D echocardiography study |
| Authors: |
Theresa Herbrand, Silke Eschenhagen, Tobias Zeus, Eva Kehmeier, Katharina Hellhammer, Verena Veulemans, Malte Kelm, Jan Balzer |
| Source: |
European Journal of Medical Research, Vol 22, Iss 1, Pp 1-11 (2017) |
| Publisher Information: |
BMC, 2017. |
| Publication Year: |
2017 |
| Collection: |
LCC:Medicine |
| Subject Terms: |
TMVR, Mitral valve insufficiency, Three-dimensional, Echocardiography, Remodeling, MitraClip®, Medicine |
| More Details: |
Abstract Background Transcatheter mitral valve repair (TMVR) has been shown to have acute effects on mitral valve geometry in patients with functional mitral regurgitation (FMR). This study investigates the impact of MitraClip® therapy-induced annular remodeling on clinical outcome and mitral regurgitation in heart failure patients. Methods TMVR was performed successfully in 45 patients with FMR. In this study, mitral valve datasets were obtained before and directly after MitraClip® implantation using three-dimensional (3D) transesophageal echocardiography, and were analyzed offline retrospectively using dedicated 3D reconstruction software. Patients underwent clinical and echocardiographic evaluation at baseline and after 6 months. At follow-up, the patients were allocated into two groups according to their improvement in New York Heart Association (NYHA) functional class: a Low Responder group with ΔNYHA |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2047-783X |
| Relation: |
http://link.springer.com/article/10.1186/s40001-017-0273-x; https://doaj.org/toc/2047-783X |
| DOI: |
10.1186/s40001-017-0273-x |
| Access URL: |
https://doaj.org/article/dd1b8c58a8a544ee9ae8dc2a82ec74bc |
| Accession Number: |
edsdoj.1b8c58a8a544ee9ae8dc2a82ec74bc |
| Database: |
Directory of Open Access Journals |
