Bibliographic Details
| Title: |
Association between inflammation‐related indicators and vertebral fracture in older adults in the United States: A cross‐sectional study based on National Health and Nutrition Examination Survey 2013–2014 |
| Authors: |
Yuwei Gou, Xiansong Xie, Heng Yin, Yucheng Wu, Yongjie Wen, Yingbo Zhang |
| Source: |
Immunity, Inflammation and Disease, Vol 12, Iss 11, Pp n/a-n/a (2024) |
| Publisher Information: |
Wiley, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Immunologic diseases. Allergy |
| Subject Terms: |
inflammation‐related index, NHANES, vertebral fracture, Immunologic diseases. Allergy, RC581-607 |
| More Details: |
Abstract Objective This study was to examine the association between inflammation‐related indexes SII (systemic immune‐inflammation index), NLR (neutrophil‐to‐lymphocyte ratio), PPN (product of platelet count and neutrophil count), and PLR (platelet‐to‐lymphocyte ratio), and the occurrence of vertebral fractures in older Americans. Methods Patients ⩾60 years of age from the 2013–2014 NHANES database were selected for this study. Restricted cubic spline models and weighted logistic regression models were used to assess the association between inflammation‐related indexes and the occurrence of vertebral fractures in older Americans. The predictive value of the inflammation‐related indexes on the occurrence of vertebral fractures was assessed using receiver operating characteristic curves (ROC). To examine the robustness of the main findings, a sensitivity analysis was conducted. Results A total of 1281 patients were included in the analysis, of whole 120 suffered vertebral fractures. Fully adjusted logistic regression showed a significant linear relationship between NLR and the occurrence of vertebral fracture in older Americans (p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2050-4527 |
| Relation: |
https://doaj.org/toc/2050-4527 |
| DOI: |
10.1002/iid3.70047 |
| Access URL: |
https://doaj.org/article/1af004af08c84cd8a9ba1d476dc514b3 |
| Accession Number: |
edsdoj.1af004af08c84cd8a9ba1d476dc514b3 |
| Database: |
Directory of Open Access Journals |
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