A national survey of antibacterial consumption in Sri Lanka.

Bibliographic Details
Title: A national survey of antibacterial consumption in Sri Lanka.
Authors: Shalini Sri Ranganathan, Chandanie Wanigatunge, G P S G Senadheera, B V S H Beneragama
Source: PLoS ONE, Vol 16, Iss 9, p e0257424 (2021)
Publisher Information: Public Library of Science (PLoS), 2021.
Publication Year: 2021
Collection: LCC:Medicine
LCC:Science
Subject Terms: Medicine, Science
More Details: IntroductionOptimizing the use of antibacterial medicines is an accepted strategy to combat the antibacterial resistance. Availability of reliable antibacterial consumption (ABC) data is a prerequisite to implement this strategy.ObjectivesTo quantify and describe the national ABC in Sri Lanka and to examine any differences in the consumption between public and private sector.MethodsThe methodology for this survey was adapted from World Health Organization (WHO) methodology for a global programme on surveillance of antimicrobial consumption. Aggregate data on national consumption of systemic antibacterials (J01- Anatomical Therapeutic Chemical Classification (ATC) for 2017 were retrospectively extracted from all available data sources and classified using ATC classification. Quantity of consumption was converted to Defined Daily Doses (DDDs). Data are presented as total consumption and comparison between the public and private sector. Selected key quality indicators of ABC were compared between these two sectors.FindingsFrom the available data sources, the total ABC in 2017 was 343.46 million DDDs. Private sector consumption accounted for 246.76 million DDDs compared to 97.96 million DDDs distributed to entire public sector by the Ministry of Health. Beta-lactam-penicillins antibacterial group accounted for 58.79% in public sector compared to 27.48% in private sector while macrolides, quinolones and other beta-lactam antibacterials accounted for 60.51% in the private compared to 28.41% in public sector. Consumption of Reserve group antibacterials was negligible, and limited to private sector. Watch category antibacterials accounted for 46%, 24% and 54% of the total, public and private sector consumption, respectively.ConclusionsA disproportionately higher use of broad spectrum and Watch category antibacterials was observed in the private sector which needs further study. This national consumption survey highlights the need and provides the opening for establishment of ABC surveillance in Sri Lanka.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1932-6203
Relation: https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0257424
Access URL: https://doaj.org/article/deac1a8c3ec042b6904b2d6cb565f417
Accession Number: edsdoj.1a8c3ec042b6904b2d6cb565f417
Database: Directory of Open Access Journals
More Details
ISSN:19326203
DOI:10.1371/journal.pone.0257424
Published in:PLoS ONE
Language:English