A New Mn(II) Complex: Magnetic Property and Application Values in Foot and Ankle Arthritis

Bibliographic Details
Title: A New Mn(II) Complex: Magnetic Property and Application Values in Foot and Ankle Arthritis
Authors: Xiaochuan Jia, Liqiang Jiang, Shubei Cui, Haidong Jia
Source: International Journal of Polymer Science, Vol 2022 (2022)
Publisher Information: Hindawi Limited, 2022.
Publication Year: 2022
Collection: LCC:Chemical technology
Subject Terms: Chemical technology, TP1-1185
More Details: The solvothermal reactions of C3-symmerical 4,4′,4′-nitrilotribenzoic acid and MnCl2 afforded a novel Mn(II) compound, and its formula is [Mn3(TCA)2(e-urea)2(DMA)2]n·n(urea)·n(DMA) (1, H3TCA=4,4′,4′-nitrilotribenzoic acid, e-urea=2-imidazaolidone, DMA=N,N′-dimethylacetamide). Magnetic property investigation of 1 indicates weak antiferromagnetic mutual effects exist between neighboring Mn(II) ions. Serial biological tests were adopted to discover new compound activity. Firstly, the enzyme-linked immunosorbent assay (ELISA) was conducted to measure the content of inflammatory cytokines released into the synovial fluid. In addition, we also studied adenosine 5′-monophosphate- (AMP-) activated protein kinase (AMPK) inflammatory signaling pathway activation through real-time reverse transcription-polymerase chain reaction (RT-PCR).
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1687-9430
Relation: https://doaj.org/toc/1687-9430
DOI: 10.1155/2022/4609960
Access URL: https://doaj.org/article/c1a1adc3d05945768de6f57cf94fc562
Accession Number: edsdoj.1a1adc3d05945768de6f57cf94fc562
Database: Directory of Open Access Journals
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More Details
ISSN:16879430
DOI:10.1155/2022/4609960
Published in:International Journal of Polymer Science
Language:English