Bibliographic Details
Title: |
A New Mn(II) Complex: Magnetic Property and Application Values in Foot and Ankle Arthritis |
Authors: |
Xiaochuan Jia, Liqiang Jiang, Shubei Cui, Haidong Jia |
Source: |
International Journal of Polymer Science, Vol 2022 (2022) |
Publisher Information: |
Hindawi Limited, 2022. |
Publication Year: |
2022 |
Collection: |
LCC:Chemical technology |
Subject Terms: |
Chemical technology, TP1-1185 |
More Details: |
The solvothermal reactions of C3-symmerical 4,4′,4′-nitrilotribenzoic acid and MnCl2 afforded a novel Mn(II) compound, and its formula is [Mn3(TCA)2(e-urea)2(DMA)2]n·n(urea)·n(DMA) (1, H3TCA=4,4′,4′-nitrilotribenzoic acid, e-urea=2-imidazaolidone, DMA=N,N′-dimethylacetamide). Magnetic property investigation of 1 indicates weak antiferromagnetic mutual effects exist between neighboring Mn(II) ions. Serial biological tests were adopted to discover new compound activity. Firstly, the enzyme-linked immunosorbent assay (ELISA) was conducted to measure the content of inflammatory cytokines released into the synovial fluid. In addition, we also studied adenosine 5′-monophosphate- (AMP-) activated protein kinase (AMPK) inflammatory signaling pathway activation through real-time reverse transcription-polymerase chain reaction (RT-PCR). |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
1687-9430 |
Relation: |
https://doaj.org/toc/1687-9430 |
DOI: |
10.1155/2022/4609960 |
Access URL: |
https://doaj.org/article/c1a1adc3d05945768de6f57cf94fc562 |
Accession Number: |
edsdoj.1a1adc3d05945768de6f57cf94fc562 |
Database: |
Directory of Open Access Journals |
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