Bibliographic Details
| Title: |
Effect of Moringa (Moringa oleifera) Leaf Flour Supplementation on Total Antioxidant Content of Sprague Dawley Rat Serum Given High-Fat Diet |
| Authors: |
Sherlin Regina Jami, Siti Fatimah-Muis, Ahmad Syauqy, Kusmiyati Tjahjono, Gemala Anjani |
| Source: |
Jurnal Gizi Indonesia: The Indonesian Journal of Nutrition, Vol 10, Iss 2, Pp 141-149 (2022) |
| Publisher Information: |
Diponegoro University, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Nutrition. Foods and food supply |
| Subject Terms: |
high fat diet, moringa oleifera leaves flour, tac, Nutrition. Foods and food supply, TX341-641 |
| More Details: |
Background: Moringa oleifera leaf is high in quercetin which can be a source of exogenous antioxidants. Together with endogenous antioxidants, both the antioxidants will be able to counteract oxidative stress conditions. Objectives: To analyze the effect of Moringa leaves flour supplementation on Total Antioxidants Content (TAC) of Sprague Dawley (SD) rat serum given a high-fat diet (HFD). Materials and Methods: A randomized control group post-test design was used on 24 SD rats which were divided into 4 groups, namely healthy control (K1), HFD (K2), supplementation with Moringa leaf flour at a dose of 100 mg/100 g BW/day (K3), and a dose of 200 mg/100 g BW/day (K4). After 28 days of supplementation, serum TAC was analyzed using the ELISA method. Data analysis used Paired-T Test, One Way ANOVA, and Post-Hoc Bonferroni follow-up test. Results: The results showed that the TAC of groups K1, K2, K3, and K4 respectively were 4.806 ± 0.239, 1.323 ± 0.292, 4.020 ± 0.239, and 5.123 ± 0.695. There was a significant difference in serum TAC (p=0.000) between supplementation groups. Significant differences in serum TAC were also found in the supplementation group compared to the HFD control group. Conclusion: Moringa leaves flour supplementation for 28 days at a dose of 200 mg/100 g BW/day increases serum total antioxidant content higher than at a dose of 100 mg/100 g BW/day. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
Indonesian |
| ISSN: |
2338-3119 |
| Relation: |
https://ejournal.undip.ac.id/index.php/jgi/article/view/42677; https://doaj.org/toc/2338-3119 |
| DOI: |
10.14710/jgi.10.2.141-149 |
| Access URL: |
https://doaj.org/article/19c821bf2f554b63a9d2f24f133e9f2c |
| Accession Number: |
edsdoj.19c821bf2f554b63a9d2f24f133e9f2c |
| Database: |
Directory of Open Access Journals |
