Bibliographic Details
| Title: |
Apico-basal cell compression regulates Lamin A/C levels in epithelial tissues |
| Authors: |
K. Venkatesan Iyer, Anna Taubenberger, Salma Ahmed Zeidan, Natalie A. Dye, Suzanne Eaton, Frank Jülicher |
| Source: |
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021) |
| Publisher Information: |
Nature Portfolio, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
The nuclear lamina bridges mechanical forces from the cytoskeleton to the nucleus, and while Lamin A/C is known to be crucial for this process, its regulation remains unclear. Here the authors show that levels of Lamin A/C scale with apico-basal compression of cells independently of tissue stiffness using Drosophila epithelial tissues and mammalian cells. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-021-22010-9 |
| Access URL: |
https://doaj.org/article/18f3dcd5533444a8967fe0f8c7d3ec46 |
| Accession Number: |
edsdoj.18f3dcd5533444a8967fe0f8c7d3ec46 |
| Database: |
Directory of Open Access Journals |
