Case Report: Tuberculosis lymphadenitis with systemic lupus erythematosus in a young woman: a case report [version 2; peer review: 2 approved, 1 not approved]

Bibliographic Details
Title: Case Report: Tuberculosis lymphadenitis with systemic lupus erythematosus in a young woman: a case report [version 2; peer review: 2 approved, 1 not approved]
Authors: Samantha Geraldine, Dewi Behtri Yanifitri, Wilia Aprilisa Utami, Yunita Arliny
Source: F1000Research, Vol 12 (2023)
Publisher Information: F1000 Research Ltd, 2023.
Publication Year: 2023
Collection: LCC:Medicine
LCC:Science
Subject Terms: Tuberculosis, TB lymphadenitis, Tuberculous lymphadenitis, Systemic Lupus Erythematosus, SLE, eng, Medicine, Science
More Details: Background: Tuberculosis is a chronic infectious disease and can be categorised into pulmonary TB and extra-pulmonary TB based on its spread. TB lymphadenitis is one of the extra-pulmonary TB diseases. Patients with a weakened immune system in systemic lupus erythematosus (SLE) have an increased incidence of TB. Case: Here we present a case report of a 21-year-old female patient with SLE diagnosed with tuberculous lymphadenitis at dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia. The patient complained of a lump in the right neck 4 months ago with a diameter of 4 cm, accompanied by fever, decreased appetite, and weight loss. Other than that, the patient also experiences joint pain, hair loss and sun sensitivity since 12 months ago. Chest radiography showed no abnormalities, and fine-needle aspiration biopsy results confirmed tuberculous lymphadenitis. Antinuclear antibody test was borderline. The patient had been taking steroids and hydroxychloroquine for the past 10 months. Currently, the patient is taking the advanced phase of antituberculosis drugs FDC. After undergoing the intensive phase of antituberculosis drugs, the submandibular lump got smaller to a diameter of 2 cm. Conclusion: TB lymphadenitis is a rare case but can occur in conditions of decreased immunity like SLE. It involves some of the immune disorders caused by the long-term use of immunosuppressive therapy.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2046-1402
Relation: https://f1000research.com/articles/12-763/v2; https://doaj.org/toc/2046-1402
DOI: 10.12688/f1000research.135076.2
Access URL: https://doaj.org/article/d18ce2ab3f874d779c8b1102b346ea38
Accession Number: edsdoj.18ce2ab3f874d779c8b1102b346ea38
Database: Directory of Open Access Journals
More Details
ISSN:20461402
DOI:10.12688/f1000research.135076.2
Published in:F1000Research
Language:English