Academic Journal
Genome-wide association study of subfoveal choroidal thickness in a longitudinal cohort of older adults
| Title: | Genome-wide association study of subfoveal choroidal thickness in a longitudinal cohort of older adults |
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| Authors: | Hyeong Min Kim, Kwangsic Joo, Minji Kim, Young Joo Park, Ji Won Han, Ki Woong Kim, Sejoon Lee, Se Joon Woo |
| Source: | Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024) |
| Publisher Information: | Nature Portfolio, 2024. |
| Publication Year: | 2024 |
| Collection: | LCC:Medicine LCC:Science |
| Subject Terms: | Age-related macular degeneration (AMD), Single nucleotide polymorphism (SNP), Choroidal thickness, GWAS, CUL3, FAM124B, Medicine, Science |
| More Details: | Abstract To identify genetic influences on subfoveal choroidal thickness of older adults using a genome-wide association study (GWAS). We recruited 300 participants from the population-based Korean Longitudinal Study on Health and Aging (KLoSHA) and Korean Longitudinal Study on Cognitive Aging and Dementia (KLOSCAD) cohort studies and 500 participants from the Bundang age-related macular degeneration (AMD) cohort study dataset. We conducted a GWAS on older adult populations in the KLoSHA and KLOSCAD cohorts. Single nucleotide polymorphisms (SNPs) associated with choroidal thickness were identified with P values |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2045-2322 |
| Relation: | https://doaj.org/toc/2045-2322 |
| DOI: | 10.1038/s41598-024-73094-4 |
| Access URL: | https://doaj.org/article/18bf0f660f84484c9a4139fc8c70fd69 |
| Accession Number: | edsdoj.18bf0f660f84484c9a4139fc8c70fd69 |
| Database: | Directory of Open Access Journals |
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| ISSN: | 20452322 |
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| DOI: | 10.1038/s41598-024-73094-4 |
| Published in: | Scientific Reports |
| Language: | English |