Bibliographic Details
| Title: |
The Association Between Intestinal Bacteria and Allergic Diseases—Cause or Consequence? |
| Authors: |
Pei Han, Jian-Qing Gu, Li-Sha Li, Xue-Yan Wang, Hong-Tian Wang, Yan Wang, Christopher Chang, Jin-Lyu Sun |
| Source: |
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021) |
| Publisher Information: |
Frontiers Media S.A., 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Microbiology |
| Subject Terms: |
allergic disorders, gut microbiome, advanced techniques, therapeutic interventions, interactions, Microbiology, QR1-502 |
| More Details: |
The incidence of allergic disorders has been increasing over the past few decades, especially in industrialized countries. Allergies can affect people of any age. The pathogenesis of allergic diseases is complex and involves genetic, epigenetic, and environmental factors, and the response to medication is very variable. For some patients, avoidance is the sole effective therapy, and only when the triggers are identifiable. In recent years, the intestinal microbiota has emerged as a significant contributor to the development of allergic diseases. However, the precise mechanisms related to the effects of the microbiome on the pathogenesis of allergic diseases are unknown. This review summarizes the recent association between allergic disorders and intestinal bacterial dysbiosis, describes the function of gut microbes in allergic disease development from both preclinical and clinical studies, discusses the factors that influence gut microbial diversity and advanced techniques used in microbial analysis. Ultimately, more studies are required to define the host-microbial relationship relevant to allergic disorders and amenable to new therapeutic interventions. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2235-2988 |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fcimb.2021.650893/full; https://doaj.org/toc/2235-2988 |
| DOI: |
10.3389/fcimb.2021.650893 |
| Access URL: |
https://doaj.org/article/a18122b881d04c33951a2b6a2b6cddee |
| Accession Number: |
edsdoj.18122b881d04c33951a2b6a2b6cddee |
| Database: |
Directory of Open Access Journals |
