Bibliographic Details
| Title: |
A proposed model of xeno-keratoplasty using 3D printing and decellularization |
| Authors: |
Xinyu Wang, Rawdah Taha Elbahrawi, Azhar Mohamud Abdukadir, Zehara Mohammed Ali, Vincent Chan, Peter R. Corridon |
| Source: |
Frontiers in Pharmacology, Vol 14 (2023) |
| Publisher Information: |
Frontiers Media S.A., 2023. |
| Publication Year: |
2023 |
| Collection: |
LCC:Therapeutics. Pharmacology |
| Subject Terms: |
cornea, xeno-keratoplasty, decellularization, recellularization, 3D bioprinting, slaughterhouse waste, Therapeutics. Pharmacology, RM1-950 |
| More Details: |
Corneal opacity is a leading cause of vision impairment and suffering worldwide. Transplantation can effectively restore vision and reduce chronic discomfort. However, there is a considerable shortage of viable corneal graft tissues. Tissue engineering may address this issue by advancing xeno-keratoplasty as a viable alternative to conventional keratoplasty. In particular, livestock decellularization strategies offer the potential to generate bioartificial ocular prosthetics in sufficient supply to match existing and projected needs. To this end, we have examined the best practices and characterizations that have supported the current state-of-the-art driving preclinical and clinical applications. Identifying the challenges that delimit activities to supplement the donor corneal pool derived from acellular scaffolds allowed us to hypothesize a model for keratoprosthesis applications derived from livestock combining 3D printing and decellularization. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1663-9812 |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fphar.2023.1193606/full; https://doaj.org/toc/1663-9812 |
| DOI: |
10.3389/fphar.2023.1193606 |
| Access URL: |
https://doaj.org/article/170249d6e62542edad0492cdf2d9d471 |
| Accession Number: |
edsdoj.170249d6e62542edad0492cdf2d9d471 |
| Database: |
Directory of Open Access Journals |
