Academic Journal
Changing epidemiology of catheter-related bloodstream infections in neutropenic oncohematological patients.
| Title: | Changing epidemiology of catheter-related bloodstream infections in neutropenic oncohematological patients. |
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| Authors: | Dajana Lendak, Pedro Puerta-Alcalde, Estela Moreno-García, Mariana Chumbita, Nicole García-Pouton, Celia Cardozo, Laura Morata, Maria Suárez-Lledó, Marta Hernández-Meneses, Lucio Ghiglione, Francesc Marco, Jose Antonio Martinez, Josep Mensa, Ivana Urošević, Alex Soriano, Carolina Garcia-Vidal |
| Source: | PLoS ONE, Vol 16, Iss 4, p e0251010 (2021) |
| Publisher Information: | Public Library of Science (PLoS), 2021. |
| Publication Year: | 2021 |
| Collection: | LCC:Medicine LCC:Science |
| Subject Terms: | Medicine, Science |
| More Details: | BackgroundWe aimed to describe the epidemiology of catheter-related bloodstream infections (CRBSIs) in onco-hematological neutropenic patients during a 25-year study period, to evaluate the risk factors for Gram-negative bacilli (GNB) CRBSI, as well as rates of inappropriate empirical antibiotic treatments (IEAT) and mortality.Materials/methodsAll consecutive episodes of CRBSIs were prospectively collected (1994-2018). Changing epidemiology was evaluated comparing five-year time spans. A multivariate regression model was built to evaluate risk factors for GNB CRBSIs.Results482 monomicrobial CRBSIs were documented. The proportion of CRBSIs among all BSIs decreased over time from 41.2% to 15.8% (pConclusionA significant shift towards GNB-CRBSIs was observed. Secondarily, and coinciding with an increasing number of GNB-MDR infections, mortality increased over time. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1932-6203 |
| Relation: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0251010&type=printable; https://doaj.org/toc/1932-6203 |
| DOI: | 10.1371/journal.pone.0251010&type=printable |
| DOI: | 10.1371/journal.pone.0251010 |
| Access URL: | https://doaj.org/article/16a95db72dcd4be4b6c3e57b867dcfbb |
| Accession Number: | edsdoj.16a95db72dcd4be4b6c3e57b867dcfbb |
| Database: | Directory of Open Access Journals |
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| ISSN: | 19326203 |
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| DOI: | 10.1371/journal.pone.0251010&type=printable |
| Published in: | PLoS ONE |
| Language: | English |