Bibliographic Details
| Title: |
Assessment of chest CT abnormalities and pulmonary function at 6-month and 1-year after hospital discharge in Chinese patients of COVID-19 pneumonia at the turn of 2022–2023 |
| Authors: |
Xingyu Fang, Jialin Li, Yijun Zhang, Wei Lv, Lin Liu, Yun Feng, Li Liu, Feng Pan, Jinping Zhang |
| Source: |
Frontiers in Medicine, Vol 12 (2025) |
| Publisher Information: |
Frontiers Media S.A., 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Medicine (General) |
| Subject Terms: |
COVID-19, SARS-CoV-2, pulmonary function, tomography, X-ray, follow-up, Medicine (General), R5-920 |
| More Details: |
ObjectiveThis study aimed to assess chest CT abnormalities and pulmonary function at 6-month and 1-year follow-ups in coronavirus disease 2019 (COVID-19) pneumonia patients of the China epidemic in the turn of 2022–2023.MethodsA total of 156 hospitalized patients with COVID-19 pneumonia admitted between 29 November 2022 and 10 February 2023 were prospectively assessed at 6-month and 1-year follow-ups. Characteristics and CT scores of pulmonary abnormalities and pulmonary function were compared between different follow-up time points. The correlation of CT abnormalities and pulmonary function at 1-year were evaluated.ResultsOver 1 year, the proportion of pulmonary abnormalities gradually decreased (initial, 100%, 156/156; 6-month, 57.1%, 89/156; and 1-year, 37.8%, 59/156; P < 0.001), whereas fibrotic changes increased (initial, 6.4%, 10/156; 6-month, 14.1%, 22/156; and 1-year, 14.7%, 23/56; P < 0.001). Compared to participants of the subgroup with nonfibrotic changes, diffusion capacity of the lung for carbon monoxide (DLCO)(P = 0.01) and DLCO less than 80% predicted (P < 0.001) showed significantly decrease in participants of the subgroup with fibrotic changes. The extent of fibrotic changes was strongly correlated with lower DLCO (r = −0.734, P < 0.001).ConclusionFibrotic changes might show a tendency to persist over time and correlate strongly with impairment of diffusion function, thus requiring more attention in future follow-ups. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2296-858X |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fmed.2025.1463320/full; https://doaj.org/toc/2296-858X |
| DOI: |
10.3389/fmed.2025.1463320 |
| Access URL: |
https://doaj.org/article/a169fa1f842040989eb39e9578091b43 |
| Accession Number: |
edsdoj.169fa1f842040989eb39e9578091b43 |
| Database: |
Directory of Open Access Journals |
