Bibliographic Details
| Title: |
Altered brain glymphatic function on diffusion-tensor MRI in patients with spontaneous intracerebral hemorrhage: an exploratory study |
| Authors: |
Xiaona Xia, Qingguo Ren, Juntao Zhang, Shuai Guan, Qingjun Jiang, Ying Wei, Rui Hua, Shen Zhao, Xiangjun Hu, Feng Shi, Xiangshui Meng |
| Source: |
Frontiers in Aging Neuroscience, Vol 16 (2024) |
| Publisher Information: |
Frontiers Media S.A., 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Neurosciences. Biological psychiatry. Neuropsychiatry |
| Subject Terms: |
spontaneous intracerebral haemorrhage, glymphatic system, diffusion tensor imaging along the perivascular space, cognitive, prognosis, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571 |
| More Details: |
ObjectivesTo investigate the function of the glymphatic system (GS) and its association with neuropsychological tests in spontaneous intracerebral hemorrhage (sICH) by diffusion tensor imaging analysis along the perivascular space (DTI-ALPS).MethodsThis retrospective study included 58 patients with sICH and 63 age- and sex-matched healthy controls (HCs). Partial correlation analyses were performed to examine the relationships between the DTI-ALPS index and radiological as well as clinical data. Mediation analyses were performed to explore the mediating role of the grey matter proportion (GM%) in the relationship between DTI-ALPS index and Montreal Cognitive Assessment (MoCA) score.ResultsSignificantly lower DTI-ALPS index values were observed in sICH compared with HCs (FDR-p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1663-4365 |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fnagi.2024.1506980/full; https://doaj.org/toc/1663-4365 |
| DOI: |
10.3389/fnagi.2024.1506980 |
| Access URL: |
https://doaj.org/article/1530e887572447aa9ccc8f75d05a1c9e |
| Accession Number: |
edsdoj.1530e887572447aa9ccc8f75d05a1c9e |
| Database: |
Directory of Open Access Journals |
