Bibliographic Details
| Title: |
Extubation timing and risk of extubation failure in aneurysmal subarachnoid hemorrhage patients |
| Authors: |
Jun Yang, Junlin Lu, Runting Li, Fa Lin, Yu Chen, Heze Han, Ruinan Li, Zhipeng Li, Haibin Zhang, Kexin Yuan, Hongliang Li, Linlin Zhang, Guangzhi Shi, Shuo Wang, Xiaolin Chen |
| Source: |
Chinese Neurosurgical Journal, Vol 10, Iss 1, Pp 1-9 (2024) |
| Publisher Information: |
BMC, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Surgery
LCC:Neurology. Diseases of the nervous system |
| Subject Terms: |
Aneurysmal subarachnoid hemorrhage, Extubation failure, Delayed cerebral ischemia, Microsurgery, Surgery, RD1-811, Neurology. Diseases of the nervous system, RC346-429 |
| More Details: |
Abstract Background The extubation time is critical during the intensive care unit stay in aneurysmal subarachnoid hemorrhage (aSAH) patients. The current conventional parameters for predicting extubation failure (EF) and extubation time may not be suitable for this population. Here, we aimed to identify factors associated with EF in aSAH patients. Methods From a single-center observational study on aSAH patients with computed tomography angiography from 2019 to 2021, patients who received microsurgery were enrolled and divided into two groups according to whether EF occurred. Multivariable logistic regression was conducted to evaluate disease severity, medical history, and extubation time differences between patients with and without EF. Results Of 335 patients included, EF occurred with a rate of 0.14. Delayed cerebral ischemia (67.4% vs. 13.5%) and acute hydrocephalus (6.5% vs. 1.4%) were frequently observed in patients with EF. Also, patients who develop EF presented higher disability (65.9% vs. 17.4%) and mortality (10.9% vs. 0.7%) rates. Multivariable analysis demonstrated that age (OR 1.038; 95% CI 1.004–1.073; P = 0.028), onset to admission time (OR 0.731; 95% CI 0.566–0.943; p = 0.016), WFNS grade > 3 (OR 4.309; 95% CI 1.639–11.330; p = 0.003), and extubation time 3 have a high risk of developing EF, which is amplified by the ultra-early extubation. Moreover, in patients with two or more risk factors, a prolonged intubation recommendation requires consideration to avoid the EF. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2057-4967 |
| Relation: |
https://doaj.org/toc/2057-4967 |
| DOI: |
10.1186/s41016-024-00384-1 |
| Access URL: |
https://doaj.org/article/14a2f74ec1754bd091bb73362db4a869 |
| Accession Number: |
edsdoj.14a2f74ec1754bd091bb73362db4a869 |
| Database: |
Directory of Open Access Journals |
