Serum ferritin is a good indicator for predicting the efficacy of adult HLH induction therapy

Bibliographic Details
Title:	Serum ferritin is a good indicator for predicting the efficacy of adult HLH induction therapy
Authors:	Zhengjie Hua, Lingbo He, Ruoxi Zhang, Menghan Liu, Zhao Wang, Yini Wang
Source:	Annals of Medicine, Vol 54, Iss 1, Pp 283-292 (2022)
Publisher Information:	Taylor & Francis Group, 2022.
Publication Year:	2022
Collection:	LCC:Medicine
Subject Terms:	adults, haemophagocytic lymphohistiocytosis, induction therapy, ferritin, efficacy, Medicine
More Details:	Background: Hemophagocytic lymphohistiocytosis (HLH) is a rare clinical syndrome with a high mortality rate. There is no biomarker to predict the early therapeutic response. Objective: Our study explores the significance of serum ferritin in predicting the response of induction therapy. Methods: We retrospectively analyzed the clinical data of 102 adult patients with HLH admitted to our hospital. These patients received HLH-94 regimen for induction therapy. The patients were divided into remission group and non-remission group according to the response of induction therapy. Results: Ferritin values between 1–4 weeks post induction were predictive of remission (p
Document Type:	article
File Description:	electronic resource
Language:	English
ISSN:	0785-3890 1365-2060 07853890
Relation:	https://doaj.org/toc/0785-3890; https://doaj.org/toc/1365-2060
DOI:	10.1080/07853890.2022.2027513
Access URL:	https://doaj.org/article/1425132422804f44824f9ee48e856f3e
Accession Number:	edsdoj.1425132422804f44824f9ee48e856f3e
Database:	Directory of Open Access Journals