Bibliographic Details
| Title: |
Medicinal Properties of Anchusa strigosa and Its Active Compounds |
| Authors: |
Ludmila Yarmolinsky, Arie Budovsky, Boris Khalfin, Leonid Yarmolinsky, Shimon Ben-Shabat |
| Source: |
Molecules, Vol 27, Iss 23, p 8239 (2022) |
| Publisher Information: |
MDPI AG, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Organic chemistry |
| Subject Terms: |
Anchusa strigosa, wound healing, anti-microbial compounds, Organic chemistry, QD241-441 |
| More Details: |
Anchusa strigosa is a widespread weed in Greece, Syria, Turkey, Lebanon, Israel, Jordan, and Iran. The purpose of this study was to identify the phytochemicals of Anchusa strigose and estimate the pro-wound healing (pro-WH) and antimicrobial activities of its active compounds. An identification of volatile compounds was performed by GC/MS analysis; HPLC, LC-ESI-MS, and MALDI-TOF-MS were also applied. Our results demonstrate that two specific combinations of compounds from A. strigosa extract significantly enhanced WH (p < 0.001). Several flavonoids of the plant extract, including quercetin 3-O-rutinoside, kaempferol, kaempferol 3-O-β-rhamnopyranosyl(1→6)-β-glucopyranoside, and kaempferol 3-O-α-rhamnopyranosyl(1→6)-β-galactopyranoside, were effective against drug-resistant microorganisms. In addition, all the above-mentioned compounds had antibiofilm activity against Escherichia coli and Salmonella enteritidis. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1420-3049 |
| Relation: |
https://www.mdpi.com/1420-3049/27/23/8239; https://doaj.org/toc/1420-3049 |
| DOI: |
10.3390/molecules27238239 |
| Access URL: |
https://doaj.org/article/139be10d6f9e4e73be54b7991bebfcdd |
| Accession Number: |
edsdoj.139be10d6f9e4e73be54b7991bebfcdd |
| Database: |
Directory of Open Access Journals |
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