Giant Mediastinal Germ Cell Tumour: An Enigma of Surgical Consideration

Bibliographic Details
Title:	Giant Mediastinal Germ Cell Tumour: An Enigma of Surgical Consideration
Authors:	Firdaus Hayati, Nurayub Mohd Ali, Levin Kesu Belani, Nornazirah Azizan, Andee Dzulkarnaen Zakaria, Mohd Ramzisham Abdul Rahman
Source:	Case Reports in Surgery, Vol 2016 (2016)
Publisher Information:	Hindawi Limited, 2016.
Publication Year:	2016
Collection:	LCC:Surgery
Subject Terms:	Surgery, RD1-811
More Details:	We present a case of 16-year-old male, who was referred from private centre for dyspnoea, fatigue, and orthopnea. The chest radiograph revealed complete opacification of left chest which was confirmed by computed tomography as a large left mediastinal mass measuring 14 × 15 × 18 cm. The diagnostic needle core biopsy revealed mixed germ cell tumour with possible combination of embryonal carcinoma, yolk sac, and teratoma. After 4 cycles of neoadjuvant BEP regime, there was initial response of tumour markers but not tumour bulk. Instead of classic median sternotomy or clamshell incision, posterolateral approach with piecemeal manner was chosen. Histology confirmed mixed germ cell tumour with residual teratomatous component without yolk sac or embryonal carcinoma component. Weighing 3.5 kg, it is one of the largest mediastinal germ cell tumours ever reported. We describe this rare and gigantic intrathoracic tumour and discuss the spectrum of surgical approach and treatment of this exceptional tumour.
Document Type:	article
File Description:	electronic resource
Language:	English
ISSN:	2090-6900 2090-6919
Relation:	https://doaj.org/toc/2090-6900; https://doaj.org/toc/2090-6919
DOI:	10.1155/2016/7615029
Access URL:	https://doaj.org/article/12e5d6f83f684d2ea35d8b8d9ced8e6f
Accession Number:	edsdoj.12e5d6f83f684d2ea35d8b8d9ced8e6f
Database:	Directory of Open Access Journals

More Details
ISSN:	20906900 20906919
DOI:	10.1155/2016/7615029
Published in:	Case Reports in Surgery
Language:	English