Objective and subjective cognitive outcomes one year after COVID‐19

Bibliographic Details
Title: Objective and subjective cognitive outcomes one year after COVID‐19
Authors: Laura Zamarian, Verena Rass, Elisabeth Goettfried, Valentina Mayr, Federico Carbone, Philipp Kindl, Margarete Delazer, Atbin Djamshidian, Alessandra Fanciulli, Philipp Mahlknecht, Beatrice Heim, Marina Peball, Alois Josef Schiefecker, Klaus Seppi, Judith Löffler‐Ragg, Ronny Beer, Bettina Pfausler, Stefan Kiechl, Raimund Helbok
Source: Annals of Clinical and Translational Neurology, Vol 11, Iss 9, Pp 2360-2371 (2024)
Publisher Information: Wiley, 2024.
Publication Year: 2024
Collection: LCC:Neurosciences. Biological psychiatry. Neuropsychiatry
LCC:Neurology. Diseases of the nervous system
Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429
More Details: Abstract Objective This study aimed to evaluate subjective cognitive, physical, and mental health symptoms as well as objective cognitive deficits in COVID‐19 patients 1 year after infection. Methods This was a cross‐sectional study. Seventy‐four patients, who contracted a SARS‐CoV‐2 infection in 2020, underwent an in‐person neuropsychological assessment in 2021. This included standardized tests of memory, attention, and executive functions. In addition, participants also responded to scales on subjective attention deficits, mental health symptoms, and fatigue. Patients' scores were compared to published norms. Results Patients (N = 74) had a median age of 56 years (42% female). According to the initial disease severity, they were classified as mild (outpatients, 32%), moderate (hospitalized, non‐ICU‐admitted, 45%), or severe (ICU‐admitted, 23%). Hospitalized patients were more often affected than outpatients. In general, deficits were most common in attention (23%), followed by memory (15%) and executive functions (3%). Patients reported increased levels of fatigue (51%), anxiety (30%), distractibility in everyday situations (20%), and depression (15%). An additional analysis suggested an association between lower scores in an attention task and hyperferritinemia. As indicated by a hierarchical regression analysis, subjective distractibility was significantly predicted by current anxiety and fatigue symptoms but not by objective attention performance (final model, adj‐R 2 = 0.588, P
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2328-9503
Relation: https://doaj.org/toc/2328-9503
DOI: 10.1002/acn3.52149
Access URL: https://doaj.org/article/124965512f964b5d9d4fbf512e17ad5b
Accession Number: edsdoj.124965512f964b5d9d4fbf512e17ad5b
Database: Directory of Open Access Journals
More Details
ISSN:23289503
DOI:10.1002/acn3.52149
Published in:Annals of Clinical and Translational Neurology
Language:English