Catheter ablation in Asian patients with atrial fibrillation and hypertrophic cardiomyopathy: electrophysiological characteristics of recurrence and long-term clinical outcomes

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Title: Catheter ablation in Asian patients with atrial fibrillation and hypertrophic cardiomyopathy: electrophysiological characteristics of recurrence and long-term clinical outcomes
Authors: Chih-Hsien Lin, Chin-Yu Lin, Fa-Po Chung, Yenn-Jiang Lin, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Tze-Fan Chao, Jo-Nan Liao, Ting-Yung Chang, Ta-Chuan Tuan, Ling Kuo, Cheng-I Wu, Chih-Min Liu, Shin-Huei Liu, Guan-Yi Li, Ming-Jen Kuo, Chi-Jen Weng, Shih-Ann Chen
Source: Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Publisher Information: Frontiers Media S.A., 2023.
Publication Year: 2023
Collection: LCC:Diseases of the circulatory (Cardiovascular) system
Subject Terms: atrial fibrillation, hypertrophic cardiomyopathy, catheter ablation, recurrence, long-term outcomes, Diseases of the circulatory (Cardiovascular) system, RC666-701
More Details: BackgroundCatheter ablation (CA) is a treatment strategy for atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM). We investigated the electrophysiological characteristics of recurrence in a tertiary referral center and compared long-term clinical outcomes after CA therapy with patients who did not undergo CA.MethodsPatients with HCM and AF who underwent CA (group 1, n = 60) or pharmacological treatment (group 2, n = 298) between 2006 and 2021 were enrolled in this study. The baseline characteristics and electrophysiological characteristics of group 1 patients were examined to elucidate the reason for the recurrence of AF after CA therapy. The clinical results of the patients in Group 1 and Group 2 were compared using a propensity score (PS)-matched method.ResultsThe most common cause of recurrence was pulmonary vein reconnection (86.5%), followed by non-pulmonary vein triggers (40.5%), cavotricuspid isthmus flutter (29.7%), and atypical flutter (24.3%). Thyroid disease (HR, 14.713; P
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2297-055X
Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2023.1135230/full; https://doaj.org/toc/2297-055X
DOI: 10.3389/fcvm.2023.1135230
Access URL: https://doaj.org/article/11d9edcdf7ac4ed28276c1699e412827
Accession Number: edsdoj.11d9edcdf7ac4ed28276c1699e412827
Database: Directory of Open Access Journals
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  Data: Catheter ablation in Asian patients with atrial fibrillation and hypertrophic cardiomyopathy: electrophysiological characteristics of recurrence and long-term clinical outcomes
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  Data: <searchLink fieldCode="AR" term="%22Chih-Hsien+Lin%22">Chih-Hsien Lin</searchLink><br /><searchLink fieldCode="AR" term="%22Chin-Yu+Lin%22">Chin-Yu Lin</searchLink><br /><searchLink fieldCode="AR" term="%22Fa-Po+Chung%22">Fa-Po Chung</searchLink><br /><searchLink fieldCode="AR" term="%22Yenn-Jiang+Lin%22">Yenn-Jiang Lin</searchLink><br /><searchLink fieldCode="AR" term="%22Shih-Lin+Chang%22">Shih-Lin Chang</searchLink><br /><searchLink fieldCode="AR" term="%22Li-Wei+Lo%22">Li-Wei Lo</searchLink><br /><searchLink fieldCode="AR" term="%22Yu-Feng+Hu%22">Yu-Feng Hu</searchLink><br /><searchLink fieldCode="AR" term="%22Tze-Fan+Chao%22">Tze-Fan Chao</searchLink><br /><searchLink fieldCode="AR" term="%22Jo-Nan+Liao%22">Jo-Nan Liao</searchLink><br /><searchLink fieldCode="AR" term="%22Ting-Yung+Chang%22">Ting-Yung Chang</searchLink><br /><searchLink fieldCode="AR" term="%22Ta-Chuan+Tuan%22">Ta-Chuan Tuan</searchLink><br /><searchLink fieldCode="AR" term="%22Ling+Kuo%22">Ling Kuo</searchLink><br /><searchLink fieldCode="AR" term="%22Cheng-I+Wu%22">Cheng-I Wu</searchLink><br /><searchLink fieldCode="AR" term="%22Chih-Min+Liu%22">Chih-Min Liu</searchLink><br /><searchLink fieldCode="AR" term="%22Shin-Huei+Liu%22">Shin-Huei Liu</searchLink><br /><searchLink fieldCode="AR" term="%22Guan-Yi+Li%22">Guan-Yi Li</searchLink><br /><searchLink fieldCode="AR" term="%22Ming-Jen+Kuo%22">Ming-Jen Kuo</searchLink><br /><searchLink fieldCode="AR" term="%22Chi-Jen+Weng%22">Chi-Jen Weng</searchLink><br /><searchLink fieldCode="AR" term="%22Shih-Ann+Chen%22">Shih-Ann Chen</searchLink>
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  Data: Frontiers in Cardiovascular Medicine, Vol 10 (2023)
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  Data: LCC:Diseases of the circulatory (Cardiovascular) system
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  Data: BackgroundCatheter ablation (CA) is a treatment strategy for atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM). We investigated the electrophysiological characteristics of recurrence in a tertiary referral center and compared long-term clinical outcomes after CA therapy with patients who did not undergo CA.MethodsPatients with HCM and AF who underwent CA (group 1, n = 60) or pharmacological treatment (group 2, n = 298) between 2006 and 2021 were enrolled in this study. The baseline characteristics and electrophysiological characteristics of group 1 patients were examined to elucidate the reason for the recurrence of AF after CA therapy. The clinical results of the patients in Group 1 and Group 2 were compared using a propensity score (PS)-matched method.ResultsThe most common cause of recurrence was pulmonary vein reconnection (86.5%), followed by non-pulmonary vein triggers (40.5%), cavotricuspid isthmus flutter (29.7%), and atypical flutter (24.3%). Thyroid disease (HR, 14.713; P
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