Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration

Bibliographic Details
Title: Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration
Authors: Julie S. Pedersen, Marte O. Rygg, Karoline Chrøis, Elahu G. Sustarsic, Zach Gerhart-Hines, Nicolai J. Wever Albrechtsen, Reza R. Serizawa, Viggo B. Kristiansen, Astrid L. Basse, Astrid E. B. Boilesen, Beth H. Olsen, Torben Hansen, Lise Lotte Gluud, Sten Madsbad, Steen Larsen, Flemming Bendtsen, Flemming Dela
Source: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Publisher Information: Nature Portfolio, 2022.
Publication Year: 2022
Collection: LCC:Science
Subject Terms: Science
More Details: Impaired mitochondrial function in liver tissue may contribute to the pathogenesis and disease progression of nonalcoholic fatty liver disease (NAFLD). Here the authors report that patients with obesity have lower mitochondrial capacity in adipose tissues but higher capacity in the liver, without overall associations to NAFLD severity, and that bariatric surgery increases hepatic mitochondrial respiration and mitochondrial biogenesis.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-022-30629-5
Access URL: https://doaj.org/article/119ec708b79c4f869bf5be8a467b9bac
Accession Number: edsdoj.119ec708b79c4f869bf5be8a467b9bac
Database: Directory of Open Access Journals
More Details
ISSN:20411723
DOI:10.1038/s41467-022-30629-5
Published in:Nature Communications
Language:English