Bibliographic Details
Title: |
Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration |
Authors: |
Julie S. Pedersen, Marte O. Rygg, Karoline Chrøis, Elahu G. Sustarsic, Zach Gerhart-Hines, Nicolai J. Wever Albrechtsen, Reza R. Serizawa, Viggo B. Kristiansen, Astrid L. Basse, Astrid E. B. Boilesen, Beth H. Olsen, Torben Hansen, Lise Lotte Gluud, Sten Madsbad, Steen Larsen, Flemming Bendtsen, Flemming Dela |
Source: |
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022) |
Publisher Information: |
Nature Portfolio, 2022. |
Publication Year: |
2022 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
Impaired mitochondrial function in liver tissue may contribute to the pathogenesis and disease progression of nonalcoholic fatty liver disease (NAFLD). Here the authors report that patients with obesity have lower mitochondrial capacity in adipose tissues but higher capacity in the liver, without overall associations to NAFLD severity, and that bariatric surgery increases hepatic mitochondrial respiration and mitochondrial biogenesis. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-022-30629-5 |
Access URL: |
https://doaj.org/article/119ec708b79c4f869bf5be8a467b9bac |
Accession Number: |
edsdoj.119ec708b79c4f869bf5be8a467b9bac |
Database: |
Directory of Open Access Journals |