Degree and site of chromosomal instability define its oncogenic potential

Bibliographic Details
Title: Degree and site of chromosomal instability define its oncogenic potential
Authors: Wilma H. M. Hoevenaar, Aniek Janssen, Ajit I. Quirindongo, Huiying Ma, Sjoerd J. Klaasen, Antoinette Teixeira, Bastiaan van Gerwen, Nico Lansu, Folkert H. M. Morsink, G. Johan A. Offerhaus, René H. Medema, Geert J. P. L. Kops, Nannette Jelluma
Source: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Publisher Information: Nature Portfolio, 2020.
Publication Year: 2020
Collection: LCC:Science
Subject Terms: Science
More Details: Aneuploidy caused by chromosomal instability is frequently observed in cancer, but little is known about its contribution to tumor development. Here, the authors show that in the mouse intestine, the consequences of aneuploidy are exquisitely dependent on both its extent and anatomical location.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-020-15279-9
Access URL: https://doaj.org/article/118f25f0a18f4b6ea689450fb6a3c626
Accession Number: edsdoj.118f25f0a18f4b6ea689450fb6a3c626
Database: Directory of Open Access Journals
More Details
ISSN:20411723
DOI:10.1038/s41467-020-15279-9
Published in:Nature Communications
Language:English