Bibliographic Details
Title: |
Degree and site of chromosomal instability define its oncogenic potential |
Authors: |
Wilma H. M. Hoevenaar, Aniek Janssen, Ajit I. Quirindongo, Huiying Ma, Sjoerd J. Klaasen, Antoinette Teixeira, Bastiaan van Gerwen, Nico Lansu, Folkert H. M. Morsink, G. Johan A. Offerhaus, René H. Medema, Geert J. P. L. Kops, Nannette Jelluma |
Source: |
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
Publisher Information: |
Nature Portfolio, 2020. |
Publication Year: |
2020 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
Aneuploidy caused by chromosomal instability is frequently observed in cancer, but little is known about its contribution to tumor development. Here, the authors show that in the mouse intestine, the consequences of aneuploidy are exquisitely dependent on both its extent and anatomical location. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-020-15279-9 |
Access URL: |
https://doaj.org/article/118f25f0a18f4b6ea689450fb6a3c626 |
Accession Number: |
edsdoj.118f25f0a18f4b6ea689450fb6a3c626 |
Database: |
Directory of Open Access Journals |