| Title: |
Clinical characterization and outcomes of impulse oscillometry-defined bronchodilator response: an ECOPD cohort-based study |
| Authors: |
Lifei Lu, Fan Wu, Jieqi Peng, Xiaohui Wu, Xiangqing Hou, Youlan Zheng, Huajing Yang, Zhishan Deng, Cuiqiong Dai, Ningning Zhao, Kunning Zhou, Qi Wan, Gaoying Tang, Jiangyu Cui, Shuqing Yu, Xiangwen Luo, Changli Yang, Shengtang Chen, Pixin Ran, Yumin Zhou |
| Source: |
Respiratory Research, Vol 25, Iss 1, Pp 1-12 (2024) |
| Publisher Information: |
BMC, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Diseases of the respiratory system |
| Subject Terms: |
Impulse oscillometry, Bronchodilator response, Small airway dysfunction, Decline in lung function, Acute exacerbations, Diseases of the respiratory system, RC705-779 |
| More Details: |
Abstract Background The clinical significance of the impulse oscillometry-defined small airway bronchodilator response (IOS-BDR) is not well-known. Accordingly, this study investigated the clinical characteristics of IOS-BDR and explored the association between lung function decline, acute respiratory exacerbations, and IOS-BDR. Methods Participants were recruited from an Early Chronic Obstructive Pulmonary Disease (ECOPD) cohort subset and were followed up for two years with visits at baseline, 12 months, and 24 months. Chronic obstructive pulmonary disease (COPD) was defined as a post-bronchodilator forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) ratio |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1465-993X |
| Relation: |
https://doaj.org/toc/1465-993X |
| DOI: |
10.1186/s12931-024-02765-7 |
| Access URL: |
https://doaj.org/article/d118a1a1f60940ac8982194e2dfc5a1a |
| Accession Number: |
edsdoj.118a1a1f60940ac8982194e2dfc5a1a |
| Database: |
Directory of Open Access Journals |
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