Bibliographic Details
| Title: |
Relationship between CMR-derived parameters of ischemia/reperfusion injury and the timing of CMR after reperfused ST-segment elevation myocardial infarction |
| Authors: |
Pier-Giorgio Masci, Anna Giulia Pavon, Olivier Muller, Juan-Fernando Iglesias, Gabriella Vincenti, Pierre Monney, Brahim Harbaoui, Eric Eeckhout, Juerg Schwitter |
| Source: |
Journal of Cardiovascular Magnetic Resonance, Vol 20, Iss 1, Pp 1-10 (2018) |
| Publisher Information: |
Elsevier, 2018. |
| Publication Year: |
2018 |
| Collection: |
LCC:Diseases of the circulatory (Cardiovascular) system |
| Subject Terms: |
Myocardial infarction, Cardiovascular magnetic resonance, T2-mapping, T1-mapping, Extracellular volume, Myocardial edema, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| More Details: |
Abstract Background To investigate the influence of cardiovascular magnetic resonance (CMR) timing after reperfusion on CMR-derived parameters of ischemia/reperfusion (I/R) injury in patients with ST-segment elevation myocardial infarction (STEMI). Methods The study included 163 reperfused STEMI patients undergoing CMR during the index hospitalization. Patients were divided according to the time between revascularization and CMR (Trevasc-CMR: Tertile-1 ≤ 43; 43 93 h). T2-mapping derived area-at-risk (AAR) and intramyocardial-hemorrhage (IMH), and late gadolinium enhancement (LGE)-derived infarct size (IS) and microvascular obstruction (MVO) were quantified. T1-mapping was performed before and > 15 min after Gd-based contrast-agent administration yielding extracellular volume (ECV) of infarct. Results Main factors influencing I/R injury were homogenously balanced across Trevasc-CMR tertiles. T2 values of infarct and remote regions increased with increasing Trevasc-CMR tertiles (infarct: 60.0 ± 4.9 vs 63.5 ± 5.6 vs 64.8 ± 7.5 ms; P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1532-429X |
| Relation: |
http://link.springer.com/article/10.1186/s12968-018-0474-7; https://doaj.org/toc/1532-429X |
| DOI: |
10.1186/s12968-018-0474-7 |
| Access URL: |
https://doaj.org/article/11420bd9ae984cb089e17d201119eee4 |
| Accession Number: |
edsdoj.11420bd9ae984cb089e17d201119eee4 |
| Database: |
Directory of Open Access Journals |
