Bibliographic Details
| Title: |
The prognostic role of RBP-4 and adiponectin in patients with peripheral arterial disease undergoing lower limb endovascular revascularization |
| Authors: |
Nikolaos P. E. Kadoglou, Emmanouil Korakas, Christos Karkos, Eirini Maratou, Ioannis Kanonidis, Panagiotis Plotas, Nikolaos Papanas, Paraskevi Moutsatsou, Ignatios Ikonomidis, Vaia Lambadiari |
| Source: |
Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-9 (2021) |
| Publisher Information: |
BMC, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Diseases of the circulatory (Cardiovascular) system |
| Subject Terms: |
RBP4, Adiponectin, Peripheral artery disease, MACE, Inflammation, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| More Details: |
Abstract Background RBP4 is an adipokine with an established role in atherosclerosis, while adiponectin has unique anti-inflammatory properties. We investigated the association of RBP4 and adiponectin with the presence of symptomatic peripheral artery disease (PAD) and their possible prognostic role in major adverse cardiovascular events (MACE). Methods We enrolled 168 consecutive patients with symptomatic, established PAD, requiring revascularization by endovascular means of any or both of their lower limbs. 88 age- and sex-matched subjects with less than 2 classical cardiovascular risk factors served as controls. Clinical parameters, glycemic and lipid profile, RBP4 and adiponectin levels were assayed. The occurrence of MACE was recorded during the 6-month follow-up and patients were assigned to MACE and non-MACE subgroups. Results The presence of symptomatic PAD was significantly correlated with age, diabetes, hsCRP, RBP4 and low adiponectin levels (p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1475-2840 |
| Relation: |
https://doaj.org/toc/1475-2840 |
| DOI: |
10.1186/s12933-021-01411-6 |
| Access URL: |
https://doaj.org/article/11216b66928f4d9ca8345b7c32066a75 |
| Accession Number: |
edsdoj.11216b66928f4d9ca8345b7c32066a75 |
| Database: |
Directory of Open Access Journals |
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