Academic Journal
Effect of 10-Valent Pneumococcal Vaccine on Pneumonia among Children, Brazil
| Title: | Effect of 10-Valent Pneumococcal Vaccine on Pneumonia among Children, Brazil |
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| Authors: | Eliane Terezinha Afonso, Ruth Minamisava, Ana Luiza Bierrenbach, Juan Jose Cortez Escalante, Airlane Pereira Alencar, Carla Magda Domingues, Otaliba Libanio Morais-Neto, Cristiana Maria Toscano, Ana Lucia Andrade |
| Source: | Emerging Infectious Diseases, Vol 19, Iss 4, Pp 589-597 (2013) |
| Publisher Information: | Centers for Disease Control and Prevention, 2013. |
| Publication Year: | 2013 |
| Collection: | LCC:Medicine LCC:Infectious and parasitic diseases |
| Subject Terms: | Pneumonia, pneumococcal vaccines, PCV10, time-series analysis, vaccination, hospitalization, Medicine, Infectious and parasitic diseases, RC109-216 |
| More Details: | Pneumonia is most problematic for children in developing countries. In 2010, Brazil introduced a 10-valent pneumococcal conjugate vaccine (PCV10) to its National Immunization Program. To assess the vaccine’s effectiveness for preventing pneumonia, we analyzed rates of hospitalization among children 2–24 months of age who had pneumonia from all causes from January 2005 through August 2011. We used data from the National Hospitalization Information System to conduct an interrupted time-series analysis for 5 cities in Brazil that had good data quality and high PCV10 vaccination coverage. Of the 197,975 hospitalizations analyzed, 30% were for pneumonia. Significant declines in hospitalizations for pneumonia were noted in Belo Horizonte (28.7%), Curitiba (23.3%), and Recife (27.4%) but not in São Paulo and Porto Alegre. However, in the latter 2 cities, vaccination coverage was less than that in the former 3. Overall, 1 year after introduction of PCV10, hospitalizations of children for pneumonia were reduced. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1080-6040 1080-6059 |
| Relation: | https://wwwnc.cdc.gov/eid/article/19/4/12-1198_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059 |
| DOI: | 10.3201/eid1904.121198 |
| Access URL: | https://doaj.org/article/10602accd46a46148231fbb9312a9e58 |
| Accession Number: | edsdoj.10602accd46a46148231fbb9312a9e58 |
| Database: | Directory of Open Access Journals |
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| ISSN: | 10806040 10806059 |
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| DOI: | 10.3201/eid1904.121198 |
| Published in: | Emerging Infectious Diseases |
| Language: | English |