Bibliographic Details
| Title: |
Effectiveness of spinal cord stimulation in diabetic patients with chronic limb-threatening ischemia: small cohort study |
| Authors: |
Anna E. Cyrek, Dietrich Koch, Arkadius Pacha, Sonia Radunz |
| Source: |
Frontiers in Surgery, Vol 11 (2024) |
| Publisher Information: |
Frontiers Media S.A., 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Surgery |
| Subject Terms: |
critical limb-threatening ischemia, peripheral arterial disease, neuromodulation, long-term results, limb salvage, quality of life, Surgery, RD1-811 |
| More Details: |
BackgroundChronic limb-threatening ischemia (CLTI) is the most severe form of peripheral artery disease (PAD). Patients with diabetes mellitus (DM) have a faster progression of PAD and a fourfold increased risk of CLTI compared to patients without DM. Epidural spinal cord stimulation (SCS) has been used as a method to improve microcirculation, relieve ischemic pain and reduce the number of amputations in patients with PAD. This is a retrospective small cohort analysis of patients with diabetes and the long-term treatment effect of spinal cord stimulation.MethodsAs the main outcome of the study, we evaluated the survival and amputation of 13 diabetic patients with chronic lower-limb ischemia who were not eligible for surgical or interventional therapy. Secondary outcomes included ankle-brachial index (ABI), ischemic pain intensity, quality of life, use of analgesic medications and skin wound outcomes analyzed during long-term follow-up.ResultsBetween January 2010 and January 2017, 13 patients underwent SCS implantation in our vascular center. At 1-year follow-up, the limb salvage rate was 92.3% (12 of 13 patients), and limb ulcers healed in 75% of patients (6/8). No patient died during the one-year follow-up. A total of 4 of patients (31%) experienced major amputation during long-term follow-up, all of them were Fontaine stage IV. Pain intensity and quality of life improved significantly at 6-month follow-up (p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2296-875X |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fsurg.2024.1451622/full; https://doaj.org/toc/2296-875X |
| DOI: |
10.3389/fsurg.2024.1451622 |
| Access URL: |
https://doaj.org/article/10513798cf494f23ac305aa2012d7b9d |
| Accession Number: |
edsdoj.10513798cf494f23ac305aa2012d7b9d |
| Database: |
Directory of Open Access Journals |
