Bibliographic Details
| Title: |
The combination of living Bifidobacterium, Lactobacillus, and Streptococcus improves social ranking and relieves anxiety‐like behaviors in competitive mice in a social dominance tube test |
| Authors: |
Jianping Xie, Yun Yuan, Heng Tan, Yufan Bai, Qingyue Zheng, Lin Mao, Yushan Wu, Ling Wang, Wenhui Da, Qingyan Ye, Suting Zhang, Jing Wang, Wenyao Yin, Yujing Bian, Wenjie Ma, Lanchun Zhang, Rongping Zhang, Haofei Yu, Ying Guo |
| Source: |
Brain and Behavior, Vol 12, Iss 1, Pp n/a-n/a (2022) |
| Publisher Information: |
Wiley, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Neurosciences. Biological psychiatry. Neuropsychiatry |
| Subject Terms: |
anxiety, Bifidobacterium, Lactobacillus, ranking score, Streptococcus, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571 |
| More Details: |
Abstract Introduction Social rank has a profound influence on the behavior and health of humans and animals. Methods To explore the effect of a combination of living Bifidobacterium, Lactobacillus and Streptococcus (CLB) on anxiety‐ and depression‐like behaviors and social rank, mice were subjected to a social dominance tube test (SDTT). The behaviors, rank, gut microbiota, and expression of inflammatory cytokines and brain‐derived neurotrophic factor (BDNF) in the hippocampus were measured. Results The results indicated that CLB improved the SDTT ranking score of the losers and alleviated anxiety‐like behaviors of the winners. CLB decreased the level of Desulfovibrio and augmented the level of Mollicutes in the feces, increased BDNF content, and reduced the level of tumor necrosis factor‐α in the hippocampus. Conclusion These findings indicated that CLB may be used for the treatment of anxiety and improvement of the rank score via regulation of gut microbiota and anti‐inflammatory effects. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2162-3279 |
| Relation: |
https://doaj.org/toc/2162-3279 |
| DOI: |
10.1002/brb3.2453 |
| Access URL: |
https://doaj.org/article/0f789663b7ef4293a9d9f0d6c49e774d |
| Accession Number: |
edsdoj.0f789663b7ef4293a9d9f0d6c49e774d |
| Database: |
Directory of Open Access Journals |
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