Predictors of caregiver adherence to administration of amodiaquine during delivery of seasonal malaria chemoprevention in Nigeria, Burkina Faso, Chad, and Togo

Bibliographic Details
Title: Predictors of caregiver adherence to administration of amodiaquine during delivery of seasonal malaria chemoprevention in Nigeria, Burkina Faso, Chad, and Togo
Authors: Taiwo Ibinaiye, Olusola Oresanya, Chibuzo Oguoma, Adaeze Aidenagbon, Olabisi Ogunmola, Christian Rassi, Sol Richardson
Source: Malaria Journal, Vol 22, Iss 1, Pp 1-7 (2023)
Publisher Information: BMC, 2023.
Publication Year: 2023
Collection: LCC:Arctic medicine. Tropical medicine
LCC:Infectious and parasitic diseases
Subject Terms: Malaria, Seasonal malaria chemoprevention, Community engagement, Amodiaquine, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216
More Details: Abstract Background Malaria is the leading cause of morbidity and mortality among infants and children under-five in sub-Saharan Africa. In the Sahel, seasonal malaria chemoprevention (SMC) is delivered door-to-door in monthly cycles. In each cycle, children are administered sulfadoxine–pyrimethamine (SP) plus amodiaquine (AQ) on Day 1 by community distributors, and AQ on Day 2 and Day 3 by caregivers. Non-adherence to AQ administration by caregivers has implications for emergence of antimalarial resistance. Methods Predictors of non-adherence to administration of AQ on Day 2 and Day 3 among caregivers of children aged 3–59 months who had received Day 1 SP and AQ during the last 2020 SMC cycle (n = 12,730) were analysed using data from SMC coverage surveys in Nigeria, Burkina Faso and Togo, and fitting multivariate random-effects logistic regression models. Results Previous adverse reaction to SMC medicines by eligible children (OR: 0.29, 95% CI 0.24–0.36, p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1475-2875
Relation: https://doaj.org/toc/1475-2875
DOI: 10.1186/s12936-023-04576-5
Access URL: https://doaj.org/article/0f18783f7ce44e478e2738468227b6ce
Accession Number: edsdoj.0f18783f7ce44e478e2738468227b6ce
Database: Directory of Open Access Journals
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More Details
ISSN:14752875
DOI:10.1186/s12936-023-04576-5
Published in:Malaria Journal
Language:English