Bibliographic Details
| Title: |
Value of resting state electroencephalogram in the diagnosis of Alzheimer's disease |
| Authors: |
Zhou Yaxin, Shao Yuan, Wang Yuanlong, Lin Ya'nan, Zhang Liangying, Wang Yongjun |
| Source: |
Sichuan jingshen weisheng, Vol 36, Iss 4, Pp 313-319 (2023) |
| Publisher Information: |
Editorial Office of Sichuan Mental Health, 2023. |
| Publication Year: |
2023 |
| Collection: |
LCC:Psychology
LCC:Psychiatry |
| Subject Terms: |
alzheimer's disease, electroencephalography, cognitive function, correlation analysis, Psychology, BF1-990, Psychiatry, RC435-571 |
| More Details: |
BackgroundThe diagnosis of Alzheimer's disease （AD） still faces great challenges， and the advantage of electroencephalogram （EEG） diagnosis lies in its portable and non-invasive nature， so the EEG diagnosis of AD has occupied an important place in clinical research.ObjectiveTo evaluate the value of resting state EEG for AD diagnosis， and to provide references for early recognition of AD in clinical practice.MethodsClinical data of AD patients （n=59） in an Inpatient Geriatric Psychiatry Unit of Shenzhen Kangning Hospital from May 2019 to May 2022 were retrospectively analyzed， and healthy elderly individuals attending outpatient clinics at the hospital during the same period were enrolled as control group （n=54）. Eight-channel resting state EEG data were acquired， and the absolute power values in the α， β， θ and δ frequency bands and the α/θ ratio were obtained and calculated using Fast Fourier Transform （FFT）. Cognitive function assessments of patients were done by Mini-Mental State Examination （MMSE） and Montreal Cognitive Assessment （MoCA）. Spearman correlation analysis was used to examine the correlation between EEG findings and MMSE and MoCA scores of AD patienrs. Logistic regression prediction model for AD was built using currently available EEG and clinical variables， and the model performance was assessed using the receiver operating characteristic （ROC） curve and the area under curve （AUC）.ResultsThe θ-band absolute powers in the right mid-frontal （F4） and mid-lateral （F7， F8） regions were higher in AD patients than those in healthy controls， with statistically significant difference （t=-2.844， -2.825， -3.014， P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
Chinese |
| ISSN: |
1007-3256 |
| Relation: |
http://www.psychjm.net.cn/scjswszzen/ch/reader/view_abstract.aspx?file_no=202304005&flag=1; https://doaj.org/toc/1007-3256 |
| DOI: |
10.11886/scjsws20230327006 |
| Access URL: |
https://doaj.org/article/d0ec3645bfe54ab3a60165809823e42d |
| Accession Number: |
edsdoj.0ec3645bfe54ab3a60165809823e42d |
| Database: |
Directory of Open Access Journals |
