Academic Journal
Optimization of pineapple juice amount used as a negative oral contrast agent in magnetic resonance cholangiopancreatography
| Title: | Optimization of pineapple juice amount used as a negative oral contrast agent in magnetic resonance cholangiopancreatography |
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| Authors: | Matteo Renzulli, Daniele Caretti, Irene Pettinari, Maurizio Biselli, Stefano Brocchi, Alessandro Sergenti, Nicolò Brandi, Rita Golfieri |
| Source: | Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022) |
| Publisher Information: | Nature Portfolio, 2022. |
| Publication Year: | 2022 |
| Collection: | LCC:Medicine LCC:Science |
| Subject Terms: | Medicine, Science |
| More Details: | Abstract To evaluate the potential variability of Manganese (Mn2+) in commercial pineapple juice (PJ) produced in different years and to identify the optimal Mn2+ concentration in the correct amount of PJ to be administered prior to Magnetic Resonance Cholangiopancreatography (MRCP) in order to suppress the gastroduodenal (GD) liquid signal. The Mn2+ concentration in PJ produced in different years was defined using Atomic Absorption Spectrometry. The optimal Mn2+ concentration and the amount of PJ, were estimated in an in-vitro analysis, and were then prospectively tested in a population of patients who underwent MRCP. The results were compared with those achieved with the previous standard amount of PJ used in a similar population. The concentrations of Mn2+ in commercial PJ produced in different years did not differ. A total amount of 150 ml (one glass) of PJ having a high Mn2+ content (2.37 mg/dl) was sufficient for the suppression of the GD liquid signal, despite the additional dilution caused by GD liquids since it led to a final concentration of Mn2+ of 0.5–1.00 mg/dl. The optimized single-dose oral administration of 150 ml (approximately one glass) of PJ having a high Mn2+ concentration prior to MRCP was adequate to guarantee the correct amount of Mn2+ to suppress the GD signal. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2045-2322 |
| Relation: | https://doaj.org/toc/2045-2322 |
| DOI: | 10.1038/s41598-021-04609-6 |
| Access URL: | https://doaj.org/article/0e6051ad59724c27b888a5148f659463 |
| Accession Number: | edsdoj.0e6051ad59724c27b888a5148f659463 |
| Database: | Directory of Open Access Journals |
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| ISSN: | 20452322 |
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| DOI: | 10.1038/s41598-021-04609-6 |
| Published in: | Scientific Reports |
| Language: | English |