Bibliographic Details
| Title: |
Two Furanosesterterpenoids from the Sponge Luffariella variabilis |
| Authors: |
Peni Ahmadi, Masahiro Higashi, Nicole J. de Voogd, Junichi Tanaka |
| Source: |
Marine Drugs, Vol 15, Iss 8, p 249 (2017) |
| Publisher Information: |
MDPI AG, 2017. |
| Publication Year: |
2017 |
| Collection: |
LCC:Biology (General) |
| Subject Terms: |
sesterterpenoid, sponge, cytotoxicity, Biology (General), QH301-705.5 |
| More Details: |
Two new sesterterpenoids, 1 and 2, were isolated from the sponge Luffariella variabilis. Their planar structures were characterized with spectroscopic analyses. The sole chiral center of compound 1 was elucidated as 12R by comparing observed and calculated optical rotation values. The configurations of compound 2 were determined by NMR and electronic circular dichroism (ECD) studies. Furthermore, compound 2 showed cytotoxicity at IC50 1.0 µM against NBT-T2 cells. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1660-3397 |
| Relation: |
https://www.mdpi.com/1660-3397/15/8/249; https://doaj.org/toc/1660-3397 |
| DOI: |
10.3390/md15080249 |
| Access URL: |
https://doaj.org/article/0e42f987c9d24821a798aa8540947674 |
| Accession Number: |
edsdoj.0e42f987c9d24821a798aa8540947674 |
| Database: |
Directory of Open Access Journals |
