Bibliographic Details
| Title: |
Chemoradiotherapy Is Inferior to Chemotherapy Alone in Adjuvant Setting for Signet Ring Cell Containing Gastric Cancer |
| Authors: |
Yue-Ting Zhu, Xin-Zu Chen, Ye Chen, Yu-Wen Zhou, Lian-Sha Tang, De-Yun Luo, Qiu Li, Meng Qiu, Xin Wang, Dan Cao, Yu Yang, Ya-Li Shen, Zhi-Ping Li, Feng Bi, Ji-Yan Liu, Hong-Feng Gou |
| Source: |
Frontiers in Oncology, Vol 10 (2020) |
| Publisher Information: |
Frontiers Media S.A., 2020. |
| Publication Year: |
2020 |
| Collection: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: |
signet ring cell carcinoma, gastric cancer, adjuvant therapy, chemotherapy, chemoradiotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: |
BackgroundSignet ring cell containing gastric cancer (SRCGC) is a rare subtype of gastric cancer, and its adjuvant therapy is based on general gastric cancer. However, the effectiveness of radiotherapy for those SRCGC patients remains unknown.PurposeThe purpose of the study was to analyze whether the addition of radiotherapy to adjuvant chemotherapy (CT) can benefit survival in resected SRCGC patients.MethodsPatients with SRCGC, who underwent D2 gastrectomy followed by adjuvant chemotherapy or chemoradiotherapy (CRT), were retrospectively collected. According to the proportion of signet ring cells, patients were histologically classified as pure SRCGC (pSRCGC) containing 100% of signet ring cells, mixed SRCGC (mSRCGC) containing >50% of signet ring cells, and contaminated SRCGC (cSRCGC) containing |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2234-943X |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fonc.2020.570268/full; https://doaj.org/toc/2234-943X |
| DOI: |
10.3389/fonc.2020.570268 |
| Access URL: |
https://doaj.org/article/0e1e71e211f2493fa05888e637fad408 |
| Accession Number: |
edsdoj.0e1e71e211f2493fa05888e637fad408 |
| Database: |
Directory of Open Access Journals |
