Bibliographic Details
| Title: |
Improvement of Anti-TNF-α Antibody-Induced Palmoplantar Pustular Psoriasis Using a 308-nm Excimer Light |
| Authors: |
Natsuko Iga, Atsushi Otsuka, Miki Tanioka, Yoshiki Miyachi, Kenji Kabashima |
| Source: |
Case Reports in Dermatology, Vol 4, Iss 3, Pp 261-264 (2012) |
| Publisher Information: |
Karger Publishers, 2012. |
| Publication Year: |
2012 |
| Collection: |
LCC:Dermatology |
| Subject Terms: |
Anti-TNF-α antibody, Palmoplantar pustular psoriasis, Paradoxical reaction, 308-nm excimer light, Dermatology, RL1-803 |
| More Details: |
Anti-tumor necrosis factor (TNF)-α antibody is utilized in the treatment of a variety of chronic inflammatory conditions, including psoriasis. However, it can induce paradoxical development and/or exacerbation of psoriasis in the course of anti-TNF-α antibody treatment, which is sometimes refractory to conventional treatments. Herein, we report a case of refractory palmoplantar pustular psoriasis induced by anti-TNF-α antibody treatment, which was improved by treatment with a 308-nm excimer light. The 308-nm excimer light has less long-term risks than narrow-band UVB. The 308-nm excimer light may be a good therapeutic option for refractory psoriatic skin lesions induced by anti-TNF-α antibody therapy because of localized side effects without systemic problems, short length of treatment and low cumulative dosages of UV light. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1662-6567 |
| Relation: |
http://www.karger.com/Article/FullText/345468; https://doaj.org/toc/1662-6567 |
| DOI: |
10.1159/000345468 |
| Access URL: |
https://doaj.org/article/0d9f28836d734154b69febab7258e610 |
| Accession Number: |
edsdoj.0d9f28836d734154b69febab7258e610 |
| Database: |
Directory of Open Access Journals |
