Hemosiderin deposition evaluation in hemophilic ankle joints: association between US finding and gradient-recalled echo MR imaging sequence

Bibliographic Details
Title: Hemosiderin deposition evaluation in hemophilic ankle joints: association between US finding and gradient-recalled echo MR imaging sequence
Authors: Marcel Prasetyo, Ariel Elisa Mongan, Novie Amelia Chozie, Joedo Prihartono, Stefanus Imanuel Setiawan
Source: Insights into Imaging, Vol 12, Iss 1, Pp 1-7 (2021)
Publisher Information: SpringerOpen, 2021.
Publication Year: 2021
Collection: LCC:Medical physics. Medical radiology. Nuclear medicine
Subject Terms: Hemosiderin deposition, Hemophilic arthropathy, US, GRE MR imaging, Medical physics. Medical radiology. Nuclear medicine, R895-920
More Details: Abstract Background Repeated bleeding in hemophilic arthropathy (HA) may result in severe degenerative changes and joint destruction. The gradient-recalled echo (GRE) sequence MR is proved to be the best method to detect hemosiderin deposition. However, MR is not widely available in developing countries, including Indonesia. Some studies have proposed ultrasonography (US) as an alternative tool in evaluating hemophilic joint. However, there is still some disagreement on the ability of US to detect hemosiderin deposition. Objective To evaluate the association between US and GRE-sequence MR imaging in detecting hemosiderin deposition in hemophilic ankle joint. Material and methods A total of 102 sites from 17 ankle joints of 11 boys with severe hemophilia A underwent US examination using a high-frequency linear array transducer. GRE-sequence MR examination was performed in sagittal view consistent with the sites scanned by US. Both examinations were performed on the same day, but MR interpretation was performed blindly at different times. The association between US and GRE-sequences in detecting hemosiderin deposition was analyzed using McNemar’s test. Results Statistical analysis showed a significant association (p value
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1869-4101
Relation: https://doaj.org/toc/1869-4101
DOI: 10.1186/s13244-021-01050-1
Access URL: https://doaj.org/article/0d959e3383614fa394e3a6e0a5561d71
Accession Number: edsdoj.0d959e3383614fa394e3a6e0a5561d71
Database: Directory of Open Access Journals
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More Details
ISSN:18694101
DOI:10.1186/s13244-021-01050-1
Published in:Insights into Imaging
Language:English