Bibliographic Details
| Title: |
Structural basis of actin monomer re-charging by cyclase-associated protein |
| Authors: |
Tommi Kotila, Konstantin Kogan, Giray Enkavi, Siyang Guo, Ilpo Vattulainen, Bruce L. Goode, Pekka Lappalainen |
| Source: |
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
| Publisher Information: |
Nature Portfolio, 2018. |
| Publication Year: |
2018 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
Depolymerized ADP-actin monomers must be recharged with ATP for new rounds of filament assembly. Here the authors show that cyclase-associated protein (CAP) catalyzes actin nucleotide exchange in vivo and their CAP–actin complex structure reveals the molecular mechanism of CAP-mediated actin nucleotide exchange. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-018-04231-7 |
| Access URL: |
https://doaj.org/article/0d7ef003bbce4a12bf5c7b11adc2fba6 |
| Accession Number: |
edsdoj.0d7ef003bbce4a12bf5c7b11adc2fba6 |
| Database: |
Directory of Open Access Journals |
