Effects of Acupotomy on Biomechanical Characteristics of Flexor and Extensor Muscle Groups and Cartilage Degeneration in Rabbits with Knee Osteoarthritis
| Title: | Effects of Acupotomy on Biomechanical Characteristics of Flexor and Extensor Muscle Groups and Cartilage Degeneration in Rabbits with Knee Osteoarthritis |
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| Authors: | GAO Hainan, ZHANG Mengyi, LIU Xi, ZHONG Peirong, TANG Yanjuan, SHAO Xinxin, TAN Zili, ZHU Xiangyu |
| Source: | 康复学报, Pp 1-9 (2025) |
| Publisher Information: | Editorial Office of Rehabilitation Medicine, 2025. |
| Publication Year: | 2025 |
| Collection: | LCC:Medicine |
| Subject Terms: | knee osteoarthritis, cartilage degeneration, acupotomology, biomechanics, muscle physical properties, Medicine |
| More Details: | ObjectiveTo study the effects of acupotomy on the muscle function of the flexor and extensor muscle groups, and cartilage degeneration in rabbits with knee osteoarthritis, and comprehensively explore the biomechanical mechanism of acupotomy in the treatment of KOA.MethodsSixty male New Zealand rabbits were divided into a blank group, a model group, an acupotomy group, and an electroacupuncture group using the random number table method, with 15 rabbits in each group. After the modeling was completed, samples with abnormal body weight, those that had died, and those with failed modeling were excluded. Finally, 48 samples were included, with 12 samples in each group. The modified Videman method was used to establish the model for eight weeks, and the acupotomy group and the electroacupuncture group were intervened for three weeks. The Lequesne MG score was used to detect the pathological changes of KOA and explore the effect of acupotomy on the behavior of KOA rabbits. One week after the intervention ended, the Myoton Pro digital muscle function assessment system was used to detect the muscle physical characteristic values of the flexor and extensor muscle groups of rabbits in each group, including oscillation frequency, dynamic stiffness, logarithmic decrement, mechanical stress relaxation time, and Deborah number (creep). The rabbits in each group were anesthetized to death, the knee joint surfaces were observed and scored using the Peng Taiping method and the articular cartilage was isolated and stained with safranin O-fast green respectively. The morphological distribution of cartilage tissue was observed to explore the effect of acupotomy on cartilage degeneration in KOA rabbits.Results① Severity of knee arthritis：after the intervention, compared with the normal group, the Lequesne MG score of the model group was increased (PPPPPPPPPPPP |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English Chinese |
| ISSN: | 2096-0328 |
| Relation: | http://kfxb.publish.founderss.cn/thesisDetails?columnId=86670235&Fpath=home&index=0; https://doaj.org/toc/2096-0328 |
| Access URL: | https://doaj.org/article/0cca3f2a88154b288bcd53645eb819b8 |
| Accession Number: | edsdoj.0cca3f2a88154b288bcd53645eb819b8 |
| Database: | Directory of Open Access Journals |
| ISSN: | 20960328 |
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| Published in: | 康复学报 |
| Language: | English Chinese |