An atlas of Wnt activity during embryogenesis in Xenopus tropicalis.

Bibliographic Details
Title:	An atlas of Wnt activity during embryogenesis in Xenopus tropicalis.
Authors:	Caroline Borday, Karine Parain, Hong Thi Tran, Kris Vleminckx, Muriel Perron, Anne H Monsoro-Burq
Source:	PLoS ONE, Vol 13, Iss 4, p e0193606 (2018)
Publisher Information:	Public Library of Science (PLoS), 2018.
Publication Year:	2018
Collection:	LCC:Medicine LCC:Science
Subject Terms:	Medicine, Science
More Details:	Wnt proteins form a family of highly conserved secreted molecules that are critical mediators of cell-cell signaling during embryogenesis. Partial data on Wnt activity in different tissues and at different stages have been reported in frog embryos. Our objective here is to provide a coherent and detailed description of Wnt activity throughout embryo development. Using a transgenic Xenopus tropicalis line carrying a Wnt-responsive reporter sequence, we depict the spatial and temporal dynamics of canonical Wnt activity during embryogenesis. We provide a comprehensive series of in situ hybridization in whole-mount embryos and in cross-sections, from gastrula to tadpole stages, with special focus on neural tube, retina and neural crest cell development. This collection of patterns will thus constitute a valuable resource for developmental biologists to picture the dynamics of Wnt activity during development.
Document Type:	article
File Description:	electronic resource
Language:	English
ISSN:	1932-6203
Relation:	http://europepmc.org/articles/PMC5908154?pdf=render; https://doaj.org/toc/1932-6203
DOI:	10.1371/journal.pone.0193606
Access URL:	https://doaj.org/article/0bdf522920914900a251b4ac1a00b8b9
Accession Number:	edsdoj.0bdf522920914900a251b4ac1a00b8b9
Database:	Directory of Open Access Journals
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More Details
ISSN:	19326203
DOI:	10.1371/journal.pone.0193606
Published in:	PLoS ONE
Language:	English