Long-term outcomes following severe COVID-19 infection: a propensity matched cohort study

Bibliographic Details
Title: Long-term outcomes following severe COVID-19 infection: a propensity matched cohort study
Authors: Kevin G Blyth, Stefan Siebert, Iain McInnes, Malcolm Sim, Martin Shaw, Tara Quasim, Lisa Gemmell, Pamela MacTavish, Helen Devine, Joanne McPeake, Mark Henderson, Varun Sharma, Kathryn Puxty, Gillian Fleming, Justine Griffin, Pauline Grose, Philip Henderson, Lucy Hogg, Kirstin King, Peter O'Brien, Callum Rainey, Laura Strachan
Source: BMJ Open Respiratory Research, Vol 8, Iss 1 (2021)
Publisher Information: BMJ Publishing Group, 2021.
Publication Year: 2021
Collection: LCC:Medicine
LCC:Diseases of the respiratory system
Subject Terms: Medicine, Diseases of the respiratory system, RC705-779
More Details: Background There are limited data describing the long-term outcomes of severe COVID-19. We aimed to evaluate the long-term psychosocial and physical consequences of severe COVID-19 for patients.Methods We conducted a multicentre observational cohort study; between 3 and 7 months posthospital discharge, patients who had been admitted to critical care due to severe COVID-19 were invited to an established recovery service. Standardised questionnaires concerning emotional, physical and social recovery, including information on employment, were completed by patients. Using propensity score matching, we explored outcomes between patients admitted to critical care with and without COVID-19, using data from the same recovery programme.Results Between July 2020 and December 2020, 93 patients who had been admitted to critical with COVID-19 participated. Emotional dysfunction was common: 46.2% of patients had symptoms of anxiety and 34.4% symptoms of depression. At follow-up 53.7% of previously employed patients had returned to employment; there was a significant difference in return to employment across the socio-economic gradient, with lower numbers of patients from the most deprived areas returning to employment (p=0.03). 91 (97.8%) COVID-19 patients were matched with 91 non-COVID-19 patients. There were no significant differences in any measured outcomes between the two cohorts.Interpretation Emotional and social problems are common in survivors of severe COVID-19 infection. Coordinated rehabilitation is required to ensure patients make an optimal recovery.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2052-4439
Relation: https://bmjopenrespres.bmj.com/content/8/1/e001080.full; https://doaj.org/toc/2052-4439
DOI: 10.1136/bmjresp-2021-001080
Access URL: https://doaj.org/article/0b8ffbf1e45e4db996e5efc45c8b6945
Accession Number: edsdoj.0b8ffbf1e45e4db996e5efc45c8b6945
Database: Directory of Open Access Journals
More Details
ISSN:20524439
DOI:10.1136/bmjresp-2021-001080
Published in:BMJ Open Respiratory Research
Language:English