Early improvement of nailfold videocapillaroscopy abnormalities in dermatomyositis patients with anti‐NXP‐2 antibody

Bibliographic Details
Title: Early improvement of nailfold videocapillaroscopy abnormalities in dermatomyositis patients with anti‐NXP‐2 antibody
Authors: Naoki Mugii, Yasuhito Hamaguchi, Natsumi Fushida, Motoki Horii, Tasuku Kitano, Ko Fujii, Kaori Sawada, Kyosuke Oishi, Shintaro Maeda, Takashi Matsushita
Source: Journal of Cutaneous Immunology and Allergy, Vol 6, Iss 6, Pp 245-248 (2023)
Publisher Information: Frontiers Media S.A., 2023.
Publication Year: 2023
Collection: LCC:Dermatology
LCC:Immunologic diseases. Allergy
Subject Terms: anti‐NXP‐2 Ab, dermatomyositis, nailfold capillary changes, Dermatology, RL1-803, Immunologic diseases. Allergy, RC581-607
More Details: Abstract This study aimed to evaluate long‐term changes in nailfold videocapillaroscopy (NVC) findings in dermatomyositis patients with antinuclear matrix protein 2 (NXP‐2) antibody (Ab). All four patients with anti‐NXP‐2 Ab presented irregularly enlarged and reduced capillaries and hemorrhages at the initial assessment. After disease stabilization, irregularly enlarged capillaries and hemorrhages disappeared within the mean observation period of 6 months. These early improvements were not observed in patients with anti‐TIF1 Ab. The results of this study show that long‐term changes in NVC findings should be assessed using myositis‐specific Ab information.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2574-4593
Relation: https://doaj.org/toc/2574-4593
DOI: 10.1002/cia2.12334
Access URL: https://doaj.org/article/0ab835f0c0be4fb7b949f7b4adb9aa51
Accession Number: edsdoj.0ab835f0c0be4fb7b949f7b4adb9aa51
Database: Directory of Open Access Journals
More Details
ISSN:25744593
DOI:10.1002/cia2.12334
Published in:Journal of Cutaneous Immunology and Allergy
Language:English