Academic Journal
Optical Fiber Distributed Sensing Network for Thermal Mapping in Radiofrequency Ablation Neighboring a Blood Vessel
| Title: | Optical Fiber Distributed Sensing Network for Thermal Mapping in Radiofrequency Ablation Neighboring a Blood Vessel |
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| Authors: | Akbota Sametova, Sabit Kurmashev, Zhannat Ashikbayeva, Wilfried Blanc, Daniele Tosi |
| Source: | Biosensors, Vol 12, Iss 12, p 1150 (2022) |
| Publisher Information: | MDPI AG, 2022. |
| Publication Year: | 2022 |
| Collection: | LCC:Biotechnology |
| Subject Terms: | radiofrequency ablation, optical fiber sensors, distributed sensors, cancer thermotherapies, mini-invasive therapy, Biotechnology, TP248.13-248.65 |
| More Details: | Radiofrequency ablation (RFA) is a minimally invasive form of thermotherapy with great potential in cancer care, having the capability of selectively ablating tumoral masses with a surface area of several cm2. When performing RFA in the proximity of a blood vessel, the heating profile changes due to heat dissipation, perfusion, and impedance changes. In this work, we provide an experimental framework for the real-time evaluation of 2D thermal maps in RFA neighboring a blood vessel; the experimental setup is based on simultaneous scanning of multiple fibers in a distributed sensing network, achieving a spatial resolution of 2.5 × 4 mm2 in situ. We also demonstrate an increase of ablating potential when injecting an agarose gel in the tissue. Experimental results show that the heat-sink effect contributes to a reduction of the ablated region around 30–60% on average; however, the use of agarose significantly mitigates this effect, enlarging the ablated area by a significant amount, and ablating an even larger surface (+15%) in the absence of blood vessels. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 12121150 2079-6374 |
| Relation: | https://www.mdpi.com/2079-6374/12/12/1150; https://doaj.org/toc/2079-6374 |
| DOI: | 10.3390/bios12121150 |
| Access URL: | https://doaj.org/article/0a729fee327d4af2aa46cd2647a5872a |
| Accession Number: | edsdoj.0a729fee327d4af2aa46cd2647a5872a |
| Database: | Directory of Open Access Journals |
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| ISSN: | 12121150 20796374 |
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| DOI: | 10.3390/bios12121150 |
| Published in: | Biosensors |
| Language: | English |