Primary Rhabdomyosarcoma of Kidney with Local Recurrence and Liver Metastasis in Adults: A Case Report

Bibliographic Details
Title: Primary Rhabdomyosarcoma of Kidney with Local Recurrence and Liver Metastasis in Adults: A Case Report
Authors: Hamid Nasrollahi, Ali Eslahi, Ali Ariafar, Faisal Ahmed, Ahmad Monabati
Source: Journal of Kidney Cancer and VHL, Vol 9, Iss 1 (2022)
Publisher Information: Codon Publications, 2022.
Publication Year: 2022
Collection: LCC:Diseases of the genitourinary system. Urology
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Subject Terms: adult, case report, kidney, liver metastasis, pleomorphic, rhabdomyosarcoma, Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
More Details: Primary rhabdomyosarcoma (RMS) of the kidney in an adult is rare, with only a few cases published in the literature. It is a mesenchymal tumor associated with an aggressive and rapid clinical progression course. We present a case of primary renal RMS in a 58-year-old female who presented with intermittent abdominal pain in the past year. The computed tomography (CT) scan revealed a 20×25×8 cm heterogeneous solid mass in the middle pole extended to the lower pole of the right kidney. Therefore, the patient underwent a right radical nephroureterectomy. Histopathology examination and immunohistochemistry studies confirmed the diagnosis of RMS with pleomorphic components. Postoperatively, the patient was discharged without any complications and was referred to an oncologist for chemotherapy. However, a follow-up CT scan in 2 months showed widespread liver metastasis and local recurrence. The patient received Gemcitabine and Docetaxel, but her condition worsened, and she passed away 5 months later. Primary renal RMS is rare in adults. In addition, liver metastasis is uncommon and poorly understood. Hence, we describe the clinicopathologic characteristics, including clinical follow-up of our case, focusing on the disease progression, treatment, and outcome.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2203-5826
Relation: https://www.jkcvhl.com/index.php/jkcvhl/article/view/218; https://doaj.org/toc/2203-5826
DOI: 10.15586/jkcvhl.v9i1.218
Access URL: https://doaj.org/article/ae0a0593133a483d9b8a943511261def
Accession Number: edsdoj.0a0593133a483d9b8a943511261def
Database: Directory of Open Access Journals
More Details
ISSN:22035826
DOI:10.15586/jkcvhl.v9i1.218
Published in:Journal of Kidney Cancer and VHL
Language:English