Case report: A 51-year-old diabetic patient with primary bilateral macronodular adrenal hyperplasia and primary hyperparathyroidism

Bibliographic Details
Title: Case report: A 51-year-old diabetic patient with primary bilateral macronodular adrenal hyperplasia and primary hyperparathyroidism
Authors: Yuan Zhong, Tao Zhang, Fan Li, Yong Chen, Liwei Tong, Chenxi Xia, Dong Wei
Source: Frontiers in Endocrinology, Vol 15 (2024)
Publisher Information: Frontiers Media S.A., 2024.
Publication Year: 2024
Collection: LCC:Diseases of the endocrine glands. Clinical endocrinology
Subject Terms: primary bilateral macronodular adrenal hyperplasia, primary hyperparathyroidism, type 2 diabetes mellitus, Cushing’s syndrome, multiple endocrine neoplasia type 1 (MEN 1), Diseases of the endocrine glands. Clinical endocrinology, RC648-665
More Details: A 51-year-old female patient with diabetes mellitus and hypertension, exhibiting poor control of blood sugar and blood pressure, was unexpectedly found to have multiple large adrenal nodules, excessive cortisol secretion, and adrenocorticotropic hormone inhibition. Cortisol levels remained unresponsive to both low-dose and high-dose dexamethasone tests, leading to a diagnosis of primary bilateral macronodular adrenal hyperplasia. Concurrently, elevated blood calcium and parathyroid hormone levels, along with 99mTc-methoxyisobutyl isonitrile (99mTc-MIBI) imaging revealing increased 99mTc-MIBI uptake in the right inferior parathyroid gland, suggest the consideration of primary hyperparathyroidism. This case is presented in light of the uncommon clinical coexistence of primary bilateral macronodular adrenal hyperplasia and primary hyperparathyroidism.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1664-2392
Relation: https://www.frontiersin.org/articles/10.3389/fendo.2024.1383987/full; https://doaj.org/toc/1664-2392
DOI: 10.3389/fendo.2024.1383987
Access URL: https://doaj.org/article/09544ff9d9074f37a88fdaf71eeb4662
Accession Number: edsdoj.09544ff9d9074f37a88fdaf71eeb4662
Database: Directory of Open Access Journals
More Details
ISSN:16642392
DOI:10.3389/fendo.2024.1383987
Published in:Frontiers in Endocrinology
Language:English