High-speed predictions of post-burn contraction using a neural network trained on 2D-finite element simulations

Bibliographic Details
Title: High-speed predictions of post-burn contraction using a neural network trained on 2D-finite element simulations
Authors: Ginger Egberts, Fred Vermolen, Paul van Zuijlen
Source: Frontiers in Applied Mathematics and Statistics, Vol 9 (2023)
Publisher Information: Frontiers Media S.A., 2023.
Publication Year: 2023
Collection: LCC:Applied mathematics. Quantitative methods
LCC:Probabilities. Mathematical statistics
Subject Terms: machine learning, post-burn scar contraction, morphoelasticity, feed–forward neural network, online application, Monte Carlo simulations, Applied mathematics. Quantitative methods, T57-57.97, Probabilities. Mathematical statistics, QA273-280
More Details: Severe burn injuries often lead to skin contraction, leading to stresses in and around the damaged skin region. If this contraction leads to impaired joint mobility, one speaks of contracture. To optimize treatment, a mathematical model, that is based on finite element methods, is developed. Since the finite element-based simulation of skin contraction can be expensive from a computational point of view, we use machine learning to replace these simulations such that we have a cheap alternative. The current study deals with a feed-forward neural network that we trained with 2D finite element simulations based on morphoelasticity. We focus on the evolution of the scar shape, wound area, and total strain energy, a measure of discomfort, over time. The results show average goodness of fit (R2) of 0.9979 and a tremendous speedup of 1815000X. Further, we illustrate the applicability of the neural network in an online medical app that takes the patient's age into account.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2297-4687
Relation: https://www.frontiersin.org/articles/10.3389/fams.2023.1098242/full; https://doaj.org/toc/2297-4687
DOI: 10.3389/fams.2023.1098242
Access URL: https://doaj.org/article/08cc4dd934d348e7aedf7df781d8788f
Accession Number: edsdoj.08cc4dd934d348e7aedf7df781d8788f
Database: Directory of Open Access Journals
More Details
ISSN:22974687
DOI:10.3389/fams.2023.1098242
Published in:Frontiers in Applied Mathematics and Statistics
Language:English